CTBP2 anticorps (C-Term)
Aperçu rapide pour CTBP2 anticorps (C-Term) (ABIN2784279)
Antigène
Voir toutes CTBP2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Séquence
- TGRIPESLRN CVNKEFFVTS APWSVIDQQA IHPELNGATY RYPPGIVGVA
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Homologie
- Cow: 100%, Dog: 100%, Goat: 86%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against CTBP2. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human CTBP2
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 985 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CTBP2 (C-terminal Binding Protein 2 (CTBP2))
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Autre désignation
- CTBP2
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Sujet
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This gene produces alternative transcripts encoding two distinct proteins. One protein is a transcriptional repressor, while the other isoform is a major component of specialized synapses known as synaptic ribbons. Both proteins contain a NAD+ binding domain similar to NAD+-dependent 2-hydroxyacid dehydrogenases. A portion of the 3' untranslated region was used to map this gene to chromosome 21q21.3, however, it was noted that similar loci elsewhere in the genome are likely.This gene produces alternative transcripts encoding two distinct proteins. One protein is a transcriptional repressor, while the other isoform is a major component of specialized synapses known as synaptic ribbons. Both proteins contain a NAD+ binding domain similar to NAD+-dependent 2-hydroxyacid dehydrogenases. A portion of the 3' untranslated region was used to map this gene to chromosome 21q21.3, however, it was noted that similar loci elsewhere in the genome are likely. Blast analysis shows that this gene is present on chromosome 10.
Alias Symbols: -
Protein Interaction Partner: NOL4, TGIF1, HOXB5, NOL4L, FUNDC1, FOXP2, RIMBP3, LCOR, ZNF750, DMRTB1, TSHZ3, BCAS3, BAZ2B, PLCB1, IKZF2, RAI2, ZBTB18, IKZF1, CTBP1, FLI1, SUMO2, SUMO3, SPRTN, SMAD6, UBC, SUMO1, NEDD8, TRNT1, DDX19B, SGTA, DYRK1B, NRIP1, ZNF512B, C15orf39, CTPS2, PPP1R
Protein Size: 985 -
Poids moléculaire
- 106 kDa
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ID gène
- 1488
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NCBI Accession
- NM_022802, NP_073713
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UniProt
- P56545
Antigène
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