URI1 anticorps (Middle Region)

N° du produit ABIN2784320

Cet anticorps anti-URI1 Polyclonal Lapin (ABIN2784320) détecte spécifiquement URI1 dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Lapin et Cobaye.

Aperçu rapide pour URI1 anticorps (Middle Region) (ABIN2784320)

Antigène: URI1 (URI1, Prefoldin-Like Chaperone (URI1))

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Lapin, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp URI1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-URI1 anticorps

Épitope: Middle Region

Fonction: C19orf2 Antibody - middle region

Séquence: NGEYVPRKSI LKSRSRENSV CSDTSESSAA EFDDRRGVLR SISCEEATCS

Homologie: Cow: 93%, Dog: 86%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 79%, Rabbit: 100%, Rat: 80%

Attributs du produit: This is a rabbit polyclonal antibody against C19orf2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human C19orf2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP50771-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur URI1

Antigène: URI1 (URI1, Prefoldin-Like Chaperone (URI1))

Autre désignation: C19orf2

Sujet:

Background Information: The function of the C19orf2 protein remains unknown.The protein encoded by this gene binds to RNA polymerase II subunit 5 (RPB5) and negatively modulates transcription through its binding to RPB5. The encoded protein seems to have inhibitory effects on various types of activated transcription, but it requires the RPB5-binding region. This protein acts as a corepressor. It is suggested that it may require signaling processes for its function or that it negatively modulates genes in the chromatin structure. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene Name: URI1, prefoldin-like chaperone

Alternative Symbols: RMP, URI, NNX3, C19orf2, PPP1R19

Protein Name: Chromosome 19 open reading frame 2 EMBL AAH67259.1

Poids moléculaire: 55kDa

ID gène: 8725

NCBI Accession: NP_604431

UniProt: Q6NX55