DCP1B anticorps (N-Term)

N° du produit ABIN2784340

Cet anticorps Lapin Polyclonal détecte spécifiquement DCP1B dans WB. Il présente une réactivité envers Humain, Souris, Rat, Lapin, Boeuf (Vache), Chien, Cobaye, Cheval et Porc.

Aperçu rapide pour DCP1B anticorps (N-Term) (ABIN2784340)

Antigène: DCP1B (DCP1 Decapping Enzyme Homolog B (DCP1B))

Reactivité: Humain, Souris, Rat, Lapin, Boeuf (Vache), Chien, Cobaye, Cheval, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DCP1B est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-DCP1B anticorps

Épitope: N-Term

Séquence: TLDPEPQHLS LTALFGKQDK ATCQETVEPP QTLHQQQQQQ QQQQEKLPIR

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 100%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against DCP1B. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human DCP1B

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 617 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur DCP1B

Antigène: DCP1B (DCP1 Decapping Enzyme Homolog B (DCP1B))

Autre désignation: DCP1B

Sujet: DCP1B may play a role in the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. It may remove the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP.DCP1B is a core component of the mRNA decapping complex, a key factor in the regulation of mRNA decay (Lykke-Andersen, 2002 [PubMed 12417715]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-844 AY146652.1 1-844 845-2079 BC015368.2 379-1613 2080-2105 AW204088.1 3-28 c
Alias Symbols: DCP1, hDcp1b
Protein Interaction Partner: EDC3, ZFP36, UBC, E2F7, DCP1A, EDC4, PPM1A, DDX6, DCP2, KANK2, PNRC1, BAG4, EXOSC6, XRN1, LSM8, UPF2, SMAD4, HSPA1L, USP4,
Protein Size: 617

Poids moléculaire: 68 kDa

ID gène: 196513

NCBI Accession: NM_152640, NP_689853

UniProt: Q8IZD4