DCP1B anticorps (N-Term)

N° du produit ABIN2784340

Détail du produit anti-DCP1B anticorps

Antigène: DCP1B (DCP1 Decapping Enzyme Homolog B (DCP1B))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Lapin, Boeuf (Vache), Chien, Cobaye, Cheval, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DCP1B est non-conjugé

Application: Western Blotting (WB)

Séquence: TLDPEPQHLS LTALFGKQDK ATCQETVEPP QTLHQQQQQQ QQQQEKLPIR

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 100%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against DCP1B. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human DCP1B

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 617 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur DCP1B

Antigène: DCP1B (DCP1 Decapping Enzyme Homolog B (DCP1B))

Autre désignation: DCP1B (DCP1B Produits)

Synonymes: anticorps DCP1, anticorps hDcp1b, anticorps B930050E02Rik, anticorps RGD1562214, anticorps dcp1, anticorps dcp1b, anticorps mitc1l, anticorps si:ch211-87p6none, anticorps decapping mRNA 1B, anticorps decapping mRNA 1B L homeolog, anticorps DCP1B, anticorps Dcp1b, anticorps dcp1b.L, anticorps dcp1b

Sujet: DCP1B may play a role in the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. It may remove the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP.DCP1B is a core component of the mRNA decapping complex, a key factor in the regulation of mRNA decay (Lykke-Andersen, 2002 [PubMed 12417715]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-844 AY146652.1 1-844 845-2079 BC015368.2 379-1613 2080-2105 AW204088.1 3-28 c
Alias Symbols: DCP1, hDcp1b
Protein Interaction Partner: EDC3, ZFP36, UBC, E2F7, DCP1A, EDC4, PPM1A, DDX6, DCP2, KANK2, PNRC1, BAG4, EXOSC6, XRN1, LSM8, UPF2, SMAD4, HSPA1L, USP4,
Protein Size: 617

Poids moléculaire: 68 kDa

ID gène: 196513

NCBI Accession: NM_152640, NP_689853

UniProt: Q8IZD4