GTF2A1L anticorps (C-Term)
Aperçu rapide pour GTF2A1L anticorps (C-Term) (ABIN2784347)
Antigène
Voir toutes GTF2A1L AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Séquence
- RVTDDDIGEI IQVDGSGDTS SNEEIGSTRD ADENEFLGNI DGGDLKVPEE
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Homologie
- Dog: 86%, Horse: 86%, Human: 100%, Mouse: 79%, Rat: 79%
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Attributs du produit
- This is a rabbit polyclonal antibody against GTF2A1L. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human GTF2A1L
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 478 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- GTF2A1L (General Transcription Factor IIA, 1-Like (GTF2A1L))
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Autre désignation
- GTF2A1L
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Sujet
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The assembly and stability of the RNA polymerase II transcription pre-initiation complex on a eukaryotic core promoter involve the effects of TFIIA on the interaction between TATA-binding protein (TBP) and DNA. This gene encodes a germ cell-specific counterpart of the large (alpha/beta) subunit of general transcription factor TFIIA that is able to stabilize the binding of TBP to DNA and may be uniquely important to testis biology.The assembly and stability of the RNA polymerase II transcription pre-initiation complex on a eukaryotic core promoter involve the effects of TFIIA on the interaction between TATA-binding protein (TBP) and DNA. This gene encodes a germ cell-specific counterpart of the large (alpha/beta) subunit of general transcription factor TFIIA that is able to stabilize the binding of TBP to DNA and may be uniquely important to testis biology. Alternative splicing for this locus has been observed and two variants, encoding distinct isoforms, have been identified. Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (SALF), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.
Alias Symbols: ALF, MGC26254
Protein Interaction Partner: GAB1, NKX2-3, ZBTB3, TLX3, MAFF, RBFOX2, HMG20A, PAX9, SIX6, MAFG, HOXC11, HOXC9, HOXA5, TLX2, EMX2, EMX1, CEBPE, ATF4, ASCL3, GTF2A2, SUB1, ID3, CSNK2A2, CSNK2A1, TBP,
Protein Size: 478 -
Poids moléculaire
- 52 kDa
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ID gène
- 11036
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NCBI Accession
- NM_006872, NP_006863
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UniProt
- Q9UNN4
Antigène
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