PYHIN1 anticorps (N-Term)

N° du produit ABIN2784367

L’anticorps anti-PYHIN1 Polyclonal Lapin est utilisé pour la détection de PYHIN1 dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Porc et Lapin. Il a été validé pour WB.

Aperçu rapide pour PYHIN1 anticorps (N-Term) (ABIN2784367)

Antigène: PYHIN1 (Pyrin and HIN Domain Family, Member 1 (PYHIN1))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Porc, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PYHIN1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PYHIN1 anticorps

Épitope: N-Term

Fonction: PYHIN1 Antibody - N-terminal region

Séquence: ANNYKKIVLL KGLEVINDYH FRIVKSLLSN DLKLNPKMKE EYDKIQIADL

Homologie: Cow: 91%, Dog: 91%, Horse: 91%, Human: 100%, Mouse: 100%, Pig: 85%, Rabbit: 93%, Rat: 85%

Attributs du produit: This is a rabbit polyclonal antibody against PYHIN1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human PYHIN1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP50875-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur PYHIN1

Antigène: PYHIN1 (Pyrin and HIN Domain Family, Member 1 (PYHIN1))

Autre désignation: PYHIN1

Sujet:

Background Information: PYHIN1 belongs to the HIN-200 family. This protein is major mediator of the tumor suppressor activity of IFN in breast cancer cells. It promotes ubiquitination and subsequent degradation of MDM2, which leads to p53/TP53 stabilization, and HDAC1, which in turn enhances maspin expression, and impairs invasive activity of cancer cells.

Gene Name: Pyrin and HIN domain family, member 1

Alternative Symbols: IFIX

Protein Name: Pyrin and HIN domain-containing protein 1

Poids moléculaire: 55kDa

ID gène: 149628

NCBI Accession: NP_689714

UniProt: Q6K0P9