FHIT anticorps (Middle Region)

N° du produit ABIN2784442

Détail du produit anti-FHIT anticorps

Antigène: FHIT (Fragile Histidine Triad (FHIT))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Cobaye, Cheval, Poisson zèbre (Danio rerio), Chien, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FHIT est non-conjugé

Application: Western Blotting (WB)

Séquence: VHVLPRKAGD FHRNDSIYEE LQKHDKEDFP ASWRSEEEMA AEAAALRVYF

Homologie: Dog: 93%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 79%, Rabbit: 93%, Rat: 79%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against FHIT. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human FHIT

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 147 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur FHIT

Antigène: FHIT (Fragile Histidine Triad (FHIT))

Autre désignation: FHIT (FHIT Produits)

Synonymes: anticorps AP3Aase, anticorps FRA3B, anticorps FHIT, anticorps zgc:73176, anticorps AW045638, anticorps Fra14A2, anticorps LOC100223655, anticorps fragile histidine triad, anticorps fragile histidine triad gene, anticorps fragile histidine triad protein, anticorps fragile histidine triad L homeolog, anticorps FHIT, anticorps Fhit, anticorps fhit, anticorps PY07476, anticorps fhit.L

Sujet: This gene, a member of the histidine triad gene family, encodes a diadenosine 5',5'''-P1,P3-triphosphate hydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. Alternatively spliced transcript variants have been found for this gene.
Alias Symbols: AP3Aase, FRA3B
Protein Interaction Partner: FHIT, REL, MDM2, UBC, RAB40B, TRIM23, LEF1, CTNNB1, UBE2I, SRC, GSN, HSPD1, FDXR,
Protein Size: 147

Poids moléculaire: 17 kDa

ID gène: 2272

NCBI Accession: NM_002012, NP_002003

UniProt: P49789