PHC2 anticorps (N-Term)
Aperçu rapide pour PHC2 anticorps (N-Term) (ABIN2784482)
Antigène
Voir toutes PHC2 (PhC2) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Séquence
- GGSGRPTGPQ ISVYSGIPDR QTVQVIQQAL HRQPSTAAQY LQQMYAAQQQ
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
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Attributs du produit
- This is a rabbit polyclonal antibody against PHC2. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human PHC2
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 858 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PHC2 (PhC2) (Polyhomeotic Homolog 2 (Drosophila) (PhC2))
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Autre désignation
- PHC2
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Sujet
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In Drosophila melanogaster, the 'Polycomb' group (PcG) of genes are part of a cellular memory system that is responsible for the stable inheritance of gene activity. PcG proteins form a large multimeric, chromatin-associated protein complex. The protein encoded by this gene has homology to the Drosophila PcG protein 'polyhomeotic' (Ph) and is known to heterodimerize with EDR1 and colocalize with BMI1 in interphase nuclei of human cells. The specific function in human cells has not yet been determined. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: EDR2, HPH2, MGC163502, PH2
Protein Interaction Partner: FAM74A4, FAM74A1, FAM13C, FAM124A, MAGEB6, ZMAT2, ZNF417, MAB21L3, SSX2IP, TRIM41, ZGPAT, L3MBTL3, PCGF5, SPATC1L, FAM161A, ENKD1, KBTBD7, SYT16, THAP7, AEN, CARD9, CBX8, C1orf109, SFMBT1, PRPF31, PPP1R16B, KAT5, PCGF3, RWDD2B, ZBTB24, MORF4L2, RBM39, AP1
Protein Size: 858 -
Poids moléculaire
- 91 kDa
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ID gène
- 1912
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NCBI Accession
- NM_198040, NP_932157
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UniProt
- Q8IXK0
Antigène
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