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PARK7/DJ1 anticorps (C-Term)

PARK7 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Porc, Chien, Cheval, Cobaye, Lapin WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2784491
  • Antigène Voir toutes PARK7/DJ1 (PARK7) Anticorps
    PARK7/DJ1 (PARK7) (Parkinson Protein 7 (PARK7))
    Épitope
    • 21
    • 16
    • 10
    • 7
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 93
    • 70
    • 50
    • 7
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat, Boeuf (Vache), Porc, Chien, Cheval, Cobaye, Lapin
    Hôte
    • 99
    • 15
    • 2
    • 1
    Lapin
    Clonalité
    • 93
    • 24
    Polyclonal
    Conjugué
    • 71
    • 13
    • 9
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PARK7/DJ1 est non-conjugé
    Application
    • 95
    • 43
    • 31
    • 30
    • 27
    • 21
    • 20
    • 15
    • 14
    • 13
    • 5
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Séquence
    TYSENRVEKD GLILTSRGPG TSFEFALAIV EALNGKEVAA QVKAPLVLKD
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against PARK7. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the C terminal region of human PARK7
    Top Product
    Discover our top product PARK7 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 189 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    PARK7/DJ1 (PARK7) (Parkinson Protein 7 (PARK7))
    Autre désignation
    PARK7 (PARK7 Produits)
    Synonymes
    anticorps DJ-1, anticorps DJ1, anticorps CAP1, anticorps Dj1, anticorps SP22, anticorps dj1, anticorps zgc:103725, anticorps park7b, anticorps park7, anticorps park7a, anticorps Parkinsonism associated deglycase, anticorps Parkinson disease (autosomal recessive, early onset) 7, anticorps parkinson protein 7, anticorps parkinson protein 7 S homeolog, anticorps parkinson protein 7 L homeolog, anticorps PARK7, anticorps Park7, anticorps park7, anticorps park7.S, anticorps park7.L
    Sujet
    PARK7 belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7.The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene.
    Alias Symbols: DJ-1, DJ1, FLJ27376
    Protein Interaction Partner: GOPC, VHL, UBC, PARK7, NPM1, BBS1, SNCA, Bax, HIPK1, TDP2, PRDX5, PPARGC1A, FADD, PRDX2, TALDO1, SREBF2, SFPQ, PTEN, NONO, MAP3K5, HSPA4, CASP8, BAG1, ATP5J, AR, PINK1, TP53, SLC18A2, PARK2, NDUFS3, NDUFA4, ND1, MAP1B, CSN1S1, SUMO1, UBE2I, DAXX, UBA2, BC
    Protein Size: 189
    Poids moléculaire
    20 kDa
    ID gène
    11315
    NCBI Accession
    NM_007262, NP_009193
    UniProt
    Q99497
    Pathways
    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Proton Transport
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