PARK7/DJ1 anticorps (C-Term)
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- Antigène Voir toutes PARK7/DJ1 (PARK7) Anticorps
- PARK7/DJ1 (PARK7) (Parkinson Protein 7 (PARK7))
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Épitope
- C-Term
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Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Porc, Chien, Cheval, Cobaye, Lapin
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PARK7/DJ1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Séquence
- TYSENRVEKD GLILTSRGPG TSFEFALAIV EALNGKEVAA QVKAPLVLKD
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against PARK7. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human PARK7
- Top Product
- Discover our top product PARK7 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 189 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- PARK7/DJ1 (PARK7) (Parkinson Protein 7 (PARK7))
- Autre désignation
- PARK7 (PARK7 Produits)
- Synonymes
- anticorps DJ-1, anticorps DJ1, anticorps CAP1, anticorps Dj1, anticorps SP22, anticorps dj1, anticorps zgc:103725, anticorps park7b, anticorps park7, anticorps park7a, anticorps Parkinsonism associated deglycase, anticorps Parkinson disease (autosomal recessive, early onset) 7, anticorps parkinson protein 7, anticorps parkinson protein 7 S homeolog, anticorps parkinson protein 7 L homeolog, anticorps PARK7, anticorps Park7, anticorps park7, anticorps park7.S, anticorps park7.L
- Sujet
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PARK7 belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7.The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene.
Alias Symbols: DJ-1, DJ1, FLJ27376
Protein Interaction Partner: GOPC, VHL, UBC, PARK7, NPM1, BBS1, SNCA, Bax, HIPK1, TDP2, PRDX5, PPARGC1A, FADD, PRDX2, TALDO1, SREBF2, SFPQ, PTEN, NONO, MAP3K5, HSPA4, CASP8, BAG1, ATP5J, AR, PINK1, TP53, SLC18A2, PARK2, NDUFS3, NDUFA4, ND1, MAP1B, CSN1S1, SUMO1, UBE2I, DAXX, UBA2, BC
Protein Size: 189 - Poids moléculaire
- 20 kDa
- ID gène
- 11315
- NCBI Accession
- NM_007262, NP_009193
- UniProt
- Q99497
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Proton Transport
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