PPIA anticorps (Middle Region)

N° du produit ABIN2784530

Détail du produit anti-PPIA anticorps

Antigène: PPIA (Peptidylprolyl Isomerase A (Cyclophilin A) (PPIA))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Chévre, Cheval, Cobaye, Lapin, Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PPIA est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: TAKTEWLDGK HVVFGKVKEG MNIVEAMERF GSRNGKTSKK ITIADCGQLE

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Sheep: 100%

Attributs du produit: This is a rabbit polyclonal antibody against PPIA. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human PPIA

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 165 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PPIA

Antigène: PPIA (Peptidylprolyl Isomerase A (Cyclophilin A) (PPIA))

Autre désignation: PPIA (PPIA Produits)

Synonymes: anticorps Cyp1, anticorps PPIA-2, anticorps fa93g09, anticorps ppia, anticorps wu:fa93g09, anticorps wu:fb05e11, anticorps wu:fb13h02, anticorps wu:fb15a05, anticorps CYPA, anticorps CypA, anticorps Cypa, anticorps CYPH, anticorps CYCA, anticorps CyP-A, anticorps MGC75715, anticorps 2700098C05, anticorps Cphn, anticorps CyP-18, anticorps MT-ND1, anticorps MTND1, anticorps NADH1, anticorps ND1, anticorps cypA, anticorps PPIase A, anticorps ppial, anticorps wu:fj18g05, anticorps zgc:73102, anticorps zgc:86688, anticorps peptidylprolyl isomerase A, anticorps peptidylprolyl isomerase Aa (cyclophilin A), anticorps peptidylprolyl isomerase A (cyclophilin A) L homeolog, anticorps cyclophilin A, anticorps cyclophilin a, anticorps peptidylprolyl isomerase A (cyclophilin A), anticorps peptidylprolyl isomerase Ab (cyclophilin A), anticorps PPIA, anticorps ppiaa, anticorps ppia.L, anticorps Cypa, anticorps CNB01230, anticorps CNB01290, anticorps Tc00.1047053506925.300, anticorps Tb11.03.0250, anticorps CYPA, anticorps Ppia, anticorps ppia, anticorps ppiab

Sujet: PPIA is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. PPIA is a cyclosporin binding-protein and may play a role in cyclosporin A-mediated immunosuppression. The protein can also interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions.The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is a cyclosporin binding-protein. It may play a role in cyclosporin A-mediated immunosuppression. This protein can interact with several HIV proteins including p55 gag, Vpr, and capsid protein. It has been shown to be necessary for the formation of infectious HIV virions. Multiple pseudogenes that map to different chromosomes have been reported. Three alternatively spliced transcript variants encoding two distinct isoforms have been observed.
Alias Symbols: CYPA, CYPH, MGC117158, MGC12404, MGC23397
Protein Interaction Partner: LNX1, HUWE1, UBC, TCF4, FUS, gag, MDM2, RPL23A, SRPK2, SRPK1, ESR1, UBD, TERT, RAD52, VCAM1, ITGA4, FN1, HCVgp1, LIG4, PAXIP1, RB1, APP, CPLX1, SNX3, TAGLN2, SOD1, RPA2, RAD23B, PTMA, IGBP1, ENO1, AKT1, USP4, CDK2, COPS5, CUL1, CUL3, CUL4B, NEDD8, CD99, C
Protein Size: 165

Poids moléculaire: 18 kDa

ID gène: 5478

NCBI Accession: NM_021130, NP_066953

UniProt: P62937