CBX2 anticorps (N-Term)

N° du produit ABIN2784551

Cet anticorps anti-CBX2 Polyclonal Lapin (ABIN2784551) détecte spécifiquement CBX2 dans WB et IP. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Cheval, Chien, Cobaye et Lapin.

Aperçu rapide pour CBX2 anticorps (N-Term) (ABIN2784551)

Antigène: CBX2 (Chromobox Homolog 2 (CBX2))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cheval, Chien, Cobaye, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CBX2 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-CBX2 anticorps

Épitope: N-Term

Fonction: CBX2 Antibody - N-terminal region

Séquence: SSSSSSSTSS SSSSDEEDDS DLDAKRGPRG RETHPVPQKK AQILVAKPEL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against CBX2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human CBX2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8097003

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur CBX2

Antigène: CBX2 (Chromobox Homolog 2 (CBX2))

Autre désignation: CBX2

Sujet:

Background Information: CBX2 Contains 1 A.T hook DNA-binding domain and 1 chromo domain. CBX2 is a component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.

Gene Name: Chromobox homolog 2

Alternative Symbols: M33, CDCA6, SRXY5

Protein Name: Chromobox protein homolog 2

Poids moléculaire: 56kDa

ID gène: 84733

NCBI Accession: NP_005180

UniProt: Q14781