MBNL2 anticorps (Middle Region)

N° du produit ABIN2784554

Cet anticorps Lapin Polyclonal détecte spécifiquement MBNL2 dans WB. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Lapin, Poisson zèbre (Danio rerio) et Cheval.

Aperçu rapide pour MBNL2 anticorps (Middle Region) (ABIN2784554)

Antigène: MBNL2 (Muscleblind-Like 2 (MBNL2))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Lapin, Poisson zèbre (Danio rerio), Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MBNL2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MBNL2 anticorps

Épitope: Middle Region

Fonction: MBNL2 Antibody - middle region

Séquence: ENGRVIACFD SLKGRCSREN CKYLHPPTHL KTQLEINGRN NLIQQKTAAA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against MBNL2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human MBNL2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP51632-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur MBNL2

Antigène: MBNL2 (Muscleblind-Like 2 (MBNL2))

Autre désignation: MBNL2

Sujet:

Background Information: MBNL2 is a C3H-type zinc finger protein, which is similar to the Drosophila melanogaster muscleblind B protein.MBNL2 is a RNA-binding protein that binds to 5'ACACCC-3' core sequence. It binds to CUG triplet repeat expansion in myotonic dystrophy muscle cells by sequestering the target RNAs. MBNL2 seems to regulate expression and localization of ITGA3 by transporting it from the nucleus to cytoplasm. It may play a role in myotonic dystrophy pathophysiology (DM).

Gene Name: Muscleblind-like splicing regulator 2

Alternative Symbols: MBLL, MBLL39, PRO2032

Protein Name: Muscleblind-like 2 (Drosophila), isoform CRA_b EMBL EAX08969.1

Poids moléculaire: 28kDa

ID gène: 10150

NCBI Accession: NP_005748

UniProt: O95205