ABAT anticorps (Middle Region)

N° du produit ABIN2784615

Détail du produit anti-ABAT anticorps

Antigène: ABAT (4-Aminobutyrate Aminotransferase (ABAT))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Chévre, Cobaye, Cheval, Poisson zèbre (Danio rerio), Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ABAT est non-conjugé

Application: Western Blotting (WB)

Séquence: IIVEPIQSEG GDNHASDDFF RKLRDIARKH GCAFLVDEVQ TGGGCTGKFW

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against ABAT. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human ABAT

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 500 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ABAT

Antigène: ABAT (4-Aminobutyrate Aminotransferase (ABAT))

Autre désignation: ABAT (ABAT Produits)

Synonymes: anticorps cb880, anticorps fj82a01, anticorps wu:fj82a01, anticorps BA0325, anticorps PSPTO0259, anticorps PSPTO0301, anticorps PSPTO1890, anticorps GABA-AT, anticorps GABAT, anticorps NPD009, anticorps GABA-T, anticorps L-AIBAT, anticorps 9630038C02Rik, anticorps AI255750, anticorps ENSMUSG00000051226, anticorps Gabaat, anticorps Gabat, anticorps Gm9851, anticorps I54, anticorps Laibat, anticorps X61497, anticorps beta-AlaAT, anticorps 4-aminobutyrate aminotransferase, anticorps 4-aminobutyrate--2-oxoglutarate transaminase, anticorps GABA aminotransferase PLP-dependent PuuE, anticorps 4-aminobutyrate aminotransferase, mitochondrial, anticorps aspartate aminotransferase family protein, anticorps 4-aminobutyrate aminotransferase S homeolog, anticorps ABAT, anticorps abat, anticorps gabT, anticorps puuE, anticorps gabT-1, anticorps gabT-2, anticorps gabT-3, anticorps CNE01830, anticorps Mmwyl1_0047, anticorps CpipJ_CPIJ008729, anticorps KCR_RS04555, anticorps Bcenmc03_4909, anticorps Hden_0972, anticorps Dbac_2000, anticorps Mesil_2400, anticorps Trad_0121, anticorps abat.S, anticorps Abat

Sujet: 4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5-phosphate. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities.4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5-phosphate. The protein sequence is over 95 % similar to the pig protein. GABA is estimated to be present in nearly one-third of human synapses. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.
Alias Symbols: GABA-AT, GABAT, NPD009
Protein Interaction Partner: LGR4, BAG3, ALDH5A1, ABAT,
Protein Size: 500

Poids moléculaire: 55 kDa

ID gène: 18

NCBI Accession: NM_020686, NP_065737

UniProt: P80404

Pathways: Monocarboxylic Acid Catabolic Process