DCK anticorps (Middle Region)

N° du produit ABIN2784622

Cité dans 1 publication. Cet anticorps anti-DCK Polyclonal Lapin (ABIN2784622) détecte spécifiquement DCK dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Cobaye, Cheval, Porc et Poisson zèbre (Danio rerio).

Aperçu rapide pour DCK anticorps (Middle Region) (ABIN2784622)

Antigène: DCK (Deoxycytidine Kinase (DCK))

Reactivité: Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Cobaye, Cheval, Porc, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DCK est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-DCK anticorps

Épitope: Middle Region

Fonction: DCK Antibody - middle region

Séquence: ATPETCLHRI YLRGRNEEQG IPLEYLEKLH YKHESWLLHR TLKTNFDYLQ

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 93%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against DCK. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human DCK

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP51775-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-DCK (ABIN2784622)

Bieghs, Caers, De Bruyne, Van Valckenborgh, Higginbotham, Vanderkerken, Menu: "The effects of forodesine in murine and human multiple myeloma cells." dans: Advances in hematology, Vol. 2010, pp. 131895, (2010) (PubMed).

Détails sur DCK

Antigène: DCK (Deoxycytidine Kinase (DCK))

Autre désignation: DCK

Sujet:

Background Information: Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity.Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Deoxycytidine kinase

Alternative Symbols: MGC117410, MGC138632

Protein Name: Deoxycytidine kinase

Poids moléculaire: 30kDa

ID gène: 1633

NCBI Accession: NP_000779

UniProt: P27707