CCT7 anticorps (Middle Region)
Aperçu rapide pour CCT7 anticorps (Middle Region) (ABIN2784636)
Antigène
Voir toutes CCT7 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Séquence
- RAIKNDSVVA GGGAIEMELS KYLRDYSRTI PGKQQLLIGA YAKALEIIPR
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 93%, Zebrafish: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against CCT7. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human CCT7
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 543 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CCT7 (Chaperonin Containing TCP1, Subunit 7 (Eta) (CCT7))
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Autre désignation
- CCT7
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Sujet
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CCT7 is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. This gene encodes a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants encoding different isoforms have been found for this gene, but only two of them have been characterized to date.
Alias Symbols: CCT-ETA, Ccth, MGC110985, Nip7-1, TCP-1-eta, CCTH, CCTETA, NIP7-1, TCP1ETA
Protein Interaction Partner: SSSCA1, TP53, FUS, HUWE1, NEDD1, UBC, TUBG1, SUMO2, LGALS3BP, CDC20, MDM2, WWOX, ASB7, CCT3, CCT6A, PRPF40A, CCT5, CCT8, CCT2, CCT4, FBXO6, UBD, FBXW4, BAG3, HDAC6, HDAC3, ILK, CDK5, CDK2, AICDA, PAN2, METTL21B, VCAM1, FAM86B2, METTL18, PEX14, NOS2, NKX3-
Protein Size: 543 -
Poids moléculaire
- 60 kDa
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ID gène
- 10574
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NCBI Accession
- NM_006429, NP_006420
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UniProt
- Q99832
Antigène
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