Gephyrin anticorps (N-Term)
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- Antigène Voir toutes Gephyrin (GPHN) Anticorps
- Gephyrin (GPHN)
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Rat, Poisson zèbre (Danio rerio), Boeuf (Vache), Chien, Cobaye, Cheval, Lapin
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Gephyrin est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- HDELEDLPSP PPPLSPPPTT SPHKQTEDKG VQCEEEEEEK KDSGVASTED
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against GPHN. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human GPHN
- Top Product
- Discover our top product GPHN Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 736 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- Gephyrin (GPHN)
- Autre désignation
- GPHN (GPHN Produits)
- Synonymes
- anticorps 5730552E08Rik, anticorps AI662856, anticorps BC027112, anticorps C230040D23, anticorps GPH, anticorps GPHRYN, anticorps geph, anticorps Geph, anticorps GPHN, anticorps GEPH, anticorps HKPX1, anticorps gpgb1, anticorps DKFZp459M0825, anticorps gephyrin, anticorps gephyrin L homeolog, anticorps gephyrin a, anticorps Gphn, anticorps GPHN, anticorps gphn.L, anticorps gphna, anticorps PTRG_08978, anticorps VDBG_00775, anticorps Tsp_03043, anticorps gphn
- Sujet
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GPHN is a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency. Numerous alternatively spliced transcript variants encoding different isoforms have been described, however, the full-length nature of all transcript variants is not currently known. This gene encodes a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the encoded protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency. Numerous alternatively spliced transcript variants encoding different isoforms have been described, however, the full-length nature of all transcript variants is not currently known.
Alias Symbols: GEPH, GPH, GPHRYN, KIAA1385
Protein Interaction Partner: UBC, PAAF1, BRCC3, PPP4R1, ROCK2, MTA2, SPTAN1, SPATS1, KHDRBS1, GPHN, ACADVL, PCK1, Dynll1, OTUD4, PRPF4, ENAH, GLRB, DYNLL2, GABARAP, MTOR, PIN1, ARHGEF9, TUBA4A, PFN1,
Protein Size: 736 - Poids moléculaire
- 80 kDa
- ID gène
- 10243
- NCBI Accession
- NM_001024218, NP_001019389
- UniProt
- Q9NQX3
- Pathways
- Synaptic Membrane, Skeletal Muscle Fiber Development
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