DYNC1I2 anticorps (N-Term)

N° du produit ABIN2784706

Détail du produit anti-DYNC1I2 anticorps

Antigène: DYNC1I2 (Dynein, Cytoplasmic 1, Intermediate Chain 2 (DYNC1I2))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DYNC1I2 est non-conjugé

Application: Western Blotting (WB)

Séquence: VAPKPPIEPE EEKTLKKDEE NDSKAPPHEL TEEEKQQILH SEEFLSFFDH

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 92%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against DYNC1I2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human DYNC1I2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 638 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur DYNC1I2

Antigène: DYNC1I2 (Dynein, Cytoplasmic 1, Intermediate Chain 2 (DYNC1I2))

Autre désignation: DYNC1I2 (DYNC1I2 Produits)

Synonymes: anticorps dnci2, anticorps dncic1, anticorps ic2, anticorps dync1i2, anticorps im:7147021, anticorps zgc:153318, anticorps 3110079H08Rik, anticorps AW554389, anticorps Dncic2, anticorps Dnci2, anticorps DNCI2, anticorps IC2, anticorps dynein, cytoplasmic 1, intermediate chain 2, anticorps dynein, cytoplasmic 1, intermediate chain 2 S homeolog, anticorps dynein cytoplasmic 1 intermediate chain 2, anticorps dynein, cytoplasmic 1, intermediate chain 2a, anticorps dync1i2, anticorps dync1i2.S, anticorps DYNC1I2, anticorps dync1i2a, anticorps Dync1i2

Sujet: DYNC1I2 acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCNT1. Involved in membrane-transport, such as Golgi apparatus, late endosomes and lysosomes.
Alias Symbols: DNCI2, FLJ21089, FLJ90842, IC2, MGC104199, MGC111094, MGC9324
Protein Interaction Partner: DYNLRB1, TUBGCP3, SUMO2, UBC, RNF2, EIF3CL, PRUNE2, DYNC1LI1, EIF3K, SERBP1, HNRNPA0, AKAP12, EIF3G, EIF3B, EIF3A, RPS26, RPS13, RPS5, PSMD8, PSMC5, YBX1, MAP2, DYNC1LI2, DYNC1H1, DDX1, ABCF1, vpr, PEX14, VCP, ECT2, CUL3, Dynll1, Dync1i2, SRRM2, DCTN1, PN
Protein Size: 638

Poids moléculaire: 71 kDa

ID gène: 1781

NCBI Accession: NM_001378, NP_001369

UniProt: Q13409

Pathways: M Phase