CRYBA1 anticorps (N-Term)
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- Antigène Voir toutes CRYBA1 Anticorps
- CRYBA1 (Crystallin, beta A1 (CRYBA1))
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Lapin, Chien, Cobaye, Poisson zèbre (Danio rerio), Cheval
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CRYBA1 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- METQAEQQEL ETLPTTKMAQ TNPTPGSLGP WKITIYDQEN FQGKRMEFTS
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
- Attributs du produit
- This is a rabbit polyclonal antibody against CRYBA1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human CRYBA1
- Top Product
- Discover our top product CRYBA1 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 215 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- CRYBA1 (Crystallin, beta A1 (CRYBA1))
- Autre désignation
- CRYBA1 (CRYBA1 Produits)
- Synonymes
- anticorps CRYB1, anticorps CTRCT10, anticorps BA3/A1, anticorps Cryb, anticorps BA3A1C, anticorps beta-A3, anticorps cryba1, anticorps zgc:92688, anticorps CRYBA3, anticorps cryb1, anticorps zgc:92720, anticorps crystallin beta A1, anticorps crystallin, beta A1, anticorps crystallin, beta A1a, anticorps crystallin beta A1 L homeolog, anticorps crystallin, beta A1b, anticorps CRYBA1, anticorps Cryba1, anticorps cryba1a, anticorps cryba1.L, anticorps cryba1, anticorps cryba1b
- Sujet
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Crystallins are the dominant structural components of the vertebrate eye lens. Defects in CRYBA1 are the cause of congenital zonular cataract with sutural opacities (CCZS).Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families, beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Beta-crystallins, the most heterogeneous, differ by the presence of the C-terminal extension (present in the basic group, none in the acidic group). Beta-crystallins form aggregates of different sizes and are able to self-associate to form dimers or to form heterodimers with other beta-crystallins. This gene, a beta acidic group member, encodes two proteins (crystallin, beta A3 and crystallin, beta A1) from a single mRNA, the latter protein is 17 aa shorter than crystallin, beta A3 and is generated by use of an alternate translation initiation site. Deletion of exons 3 and 4 causes the autosomal dominant disease 'zonular cataract with sutural opacities'. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CRYB1
Protein Interaction Partner: RHOXF2, RBPMS, CRYBB3, CRYBB1, CRYBA1, CRYAB, CRYAA,
Protein Size: 215 - Poids moléculaire
- 25 kDa
- ID gène
- 1411
- NCBI Accession
- NM_005208, NP_005199
- UniProt
- P05813
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