SAE1 anticorps (N-Term)

N° du produit ABIN2784763

Cet anticorps Lapin Polyclonal détecte spécifiquement SAE1 dans WB. Il présente une réactivité envers Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Cobaye, Poisson zèbre (Danio rerio) et Saccharomyces cerevisiae.

Aperçu rapide pour SAE1 anticorps (N-Term) (ABIN2784763)

Antigène: SAE1 (SUMO1 Activating Enzyme Subunit 1 (SAE1))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Cobaye, Poisson zèbre (Danio rerio), Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SAE1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SAE1 anticorps

Épitope: N-Term

Séquence: MVEKEEAGGG ISEEEAAQYD RQIRLWGLEA QKRLRASRVL LVGLKGLGAE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 92%, Rat: 100%, Yeast: 86%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against SAE1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human SAE1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 346 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SAE1

Antigène: SAE1 (SUMO1 Activating Enzyme Subunit 1 (SAE1))

Autre désignation: SAE1

Sujet: Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1, MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 and UBA2 (MIM 613295) form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 9920803]).
Alias Symbols: AOS1, FLJ3091, HSPC140, SUA1, UBLE1A
Protein Interaction Partner: FUS, USP39, SUMO2, HSPA2, HSPA1A, UBC, TRMT10A, DPP9, RPRD1B, NPLOC4, OSGEP, PANK4, WDR4, CUL5, TPD52L2, SRP14, RANGAP1, PPP2R5E, MCM3, LPP, DHPS, CALU, ADSL, AARS, PDE12, TP53RK, UBE2I, UBA2, BAG3, PTK2, IL3RA, APP, SUMO1, ETV4, BCL6, UBE2E3, SUMO3, SP10
Protein Size: 346

Poids moléculaire: 38 kDa

ID gène: 10055

NCBI Accession: NM_005500, NP_005491

UniProt: Q9UBE0