SAE1 anticorps (N-Term)
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- Antigène Voir toutes SAE1 Anticorps
- SAE1 (SUMO1 Activating Enzyme Subunit 1 (SAE1))
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Cobaye, Poisson zèbre (Danio rerio), Saccharomyces cerevisiae
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SAE1 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- MVEKEEAGGG ISEEEAAQYD RQIRLWGLEA QKRLRASRVL LVGLKGLGAE
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 92%, Rat: 100%, Yeast: 86%, Zebrafish: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against SAE1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human SAE1
- Top Product
- Discover our top product SAE1 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 346 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- SAE1 (SUMO1 Activating Enzyme Subunit 1 (SAE1))
- Autre désignation
- SAE1 (SAE1 Produits)
- Synonymes
- anticorps AOS1, anticorps HSPC140, anticorps SUA1, anticorps UBLE1A, anticorps 2400010M20Rik, anticorps 2610044L12Rik, anticorps AL033372, anticorps AW743391, anticorps D7Ertd177e, anticorps Sua1, anticorps Uble1a, anticorps Aos1p, anticorps Sua1p, anticorps aos, anticorps sae2a, anticorps uble1a, anticorps wu:fa28b04, anticorps zgc:86633, anticorps SUMO1 activating enzyme subunit 1, anticorps SUMO1 activating enzyme subunit 1 L homeolog, anticorps SAE1, anticorps Sae1, anticorps sae1.L, anticorps sae1
- Sujet
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Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1, MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 and UBA2 (MIM 613295) form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 9920803]).
Alias Symbols: AOS1, FLJ3091, HSPC140, SUA1, UBLE1A
Protein Interaction Partner: FUS, USP39, SUMO2, HSPA2, HSPA1A, UBC, TRMT10A, DPP9, RPRD1B, NPLOC4, OSGEP, PANK4, WDR4, CUL5, TPD52L2, SRP14, RANGAP1, PPP2R5E, MCM3, LPP, DHPS, CALU, ADSL, AARS, PDE12, TP53RK, UBE2I, UBA2, BAG3, PTK2, IL3RA, APP, SUMO1, ETV4, BCL6, UBE2E3, SUMO3, SP10
Protein Size: 346 - Poids moléculaire
- 38 kDa
- ID gène
- 10055
- NCBI Accession
- NM_005500, NP_005491
- UniProt
- Q9UBE0
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