SAE1 anticorps (N-Term)

N° du produit ABIN2784764

L’anticorps Lapin Polyclonal anti-SAE1 a été validé pour WB. Il convient pour détecter SAE1 dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Cobaye, Cheval et Porc.

Aperçu rapide pour SAE1 anticorps (N-Term) (ABIN2784764)

Antigène: SAE1 (SUMO1 Activating Enzyme Subunit 1 (SAE1))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Cobaye, Cheval, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SAE1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SAE1 anticorps

Épitope: N-Term

Séquence: VTPEDPGAQF LIRTGSVGRN RAEASLERAQ NLNPMVDVKV DTEDIEKKPE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against SAE1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human SAE1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 346 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SAE1

Antigène: SAE1 (SUMO1 Activating Enzyme Subunit 1 (SAE1))

Autre désignation: SAE1

Sujet: Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1, MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 and UBA2 (MIM 613295) form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 9920803]).
Alias Symbols: AOS1, FLJ3091, HSPC140, SUA1, UBLE1A
Protein Interaction Partner: FUS, USP39, SUMO2, HSPA2, HSPA1A, UBC, TRMT10A, DPP9, RPRD1B, NPLOC4, OSGEP, PANK4, WDR4, CUL5, TPD52L2, SRP14, RANGAP1, PPP2R5E, MCM3, LPP, DHPS, CALU, ADSL, AARS, PDE12, TP53RK, UBE2I, UBA2, BAG3, PTK2, IL3RA, APP, SUMO1, ETV4, BCL6, UBE2E3, SUMO3, SP10
Protein Size: 346

Poids moléculaire: 38 kDa

ID gène: 10055

NCBI Accession: NM_005500, NP_005491

UniProt: Q9UBE0