ACTR1B anticorps (C-Term)

N° du produit ABIN2784773

Cité dans 1 publication. Cet anticorps anti-ACTR1B Polyclonal Lapin (ABIN2784773) détecte spécifiquement ACTR1B dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Chien, Boeuf (Vache), Lapin, Cobaye, Cheval et Poisson zèbre (Danio rerio).

Aperçu rapide pour ACTR1B anticorps (C-Term) (ABIN2784773)

Antigène: ACTR1B (ARP1 Actin-Related Protein 1 Homolog B, Centractin beta (ACTR1B))

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Lapin, Cobaye, Cheval, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ACTR1B est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ACTR1B anticorps

Épitope: C-Term

Fonction: ACTR1B Antibody - C-terminal region

Séquence: KIKISAPQER LYSTWIGGSI LASLDTFKKM WVSKKEYEED GSRAIHRKTF

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against ACTR1B. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human ACTR1B

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8094976

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-ACTR1B (ABIN2784773)

Hwang, Weng, Lin, Bau, Ko, Tsai, Tsai, Wu, Lin, Huang, Kuo: "Hypoxia-induced compensatory effect as related to Shh and HIF-1alpha in ischemia embryo rat heart." dans: Molecular and cellular biochemistry, Vol. 311, Issue 1-2, pp. 179-87, (2008) (PubMed).

Détails sur ACTR1B

Antigène: ACTR1B (ARP1 Actin-Related Protein 1 Homolog B, Centractin beta (ACTR1B))

Autre désignation: ACTR1B

Sujet:

Background Information: ACTR1B is a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein and is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. ACTR1B, like ACTR1A, is an actin-related protein. These two proteins, which are of equal length and share 90 % amino acid identity, are present in a constant ratio of approximately 1:15 in the dynactin complex.This gene encodes a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like ACTR1A, is an actin-related protein. These two proteins are of equal length and share 90 % amino acid identity. They are present in a constant ratio of approximately 1:15 in the dynactin complex.

Gene Name: ARP1 actin-related protein 1 homolog B, centractin beta (yeast)

Alternative Symbols: PC3, ARP1B, CTRN2

Protein Name: Beta-centractin

Poids moléculaire: 42kDa

ID gène: 10120

NCBI Accession: NP_005726

UniProt: P42025