HAX1 anticorps (Middle Region)

N° du produit ABIN2784796

Détail du produit anti-HAX1 anticorps

Antigène: HAX1 (HCLS1 Associated Protein X-1 (HAX1))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Cobaye, Cheval, Boeuf (Vache), Chien, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HAX1 est non-conjugé

Application: Western Blotting (WB)

Séquence: QPAPDWGSQR PFHRFDDVWP MDPHPRTRED NDLDSQVSQE GLGPVLQPQP

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 92%, Zebrafish: 91%

Attributs du produit: This is a rabbit polyclonal antibody against HAX1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human HAX1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 231 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur HAX1

Antigène: HAX1 (HCLS1 Associated Protein X-1 (HAX1))

Autre désignation: HAX1 (HAX1 Produits)

Synonymes: anticorps HAX1, anticorps hax1, anticorps HCLSBP1, anticorps HS1BP1, anticorps SCN3, anticorps HAX-1, anticorps Hs1bp1, anticorps HSP1BP-1, anticorps SIG-111, anticorps Silg111, anticorps mHAX-1s, anticorps HCLS1 associated protein X-1, anticorps HCLS1 associated X-1, anticorps HAX1, anticorps hax1, anticorps Hax1

Sujet: HAX1 is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease.
Alias Symbols: HCLSBP1, HS1BP1, SCN3
Protein Interaction Partner: ERLIN2, UBC, BIRC3, CEP250, TUBGCP2, TUBGCP3, MAPK10, HIPK1, DYRK4, ZNF420, POLR1D, ZNRD1, RBX1, STAT5B, RPA1, PPP3CC, CFTR, EWSR1, SHC1, HTRA2, NEDD4L, CUL3, CUL4A, PIDD1, SVIL, EBNA-LP, AMFR, HNF4G, AKAP10, TUBB4A, ABCC4, MATN4, EIF3D, RGS1, HSP90AB1, H
Protein Size: 231

Poids moléculaire: 25 kDa

ID gène: 10456

NCBI Accession: NM_001018837, NP_001018238

UniProt: O00165

Pathways: Regulation of Actin Filament Polymerization