RALBP1 anticorps (N-Term)

N° du produit ABIN2784844

Cet anticorps anti-RALBP1 est un anticorps Lapin Polyclonal détectant RALBP1 dans WB et IHC. Adapté pour Humain, Souris, Rat, Chien, Boeuf (Vache), Chévre, Cheval, Porc, Lapin et Cobaye.

Aperçu rapide pour RALBP1 anticorps (N-Term) (ABIN2784844)

Antigène: RALBP1 (RalA Binding Protein 1 (RALBP1))

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Chévre, Cheval, Porc, Lapin, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RALBP1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-RALBP1 anticorps

Épitope: N-Term

Séquence: MTECFLPPTS SPSEHRRVEH GSGLTRTPSS EEISPTKFPG LYRTGEPSPP

Homologie: Cow: 100%, Dog: 100%, Goat: 86%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against RALBP1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human RALBP1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 655 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur RALBP1

Antigène: RALBP1 (RalA Binding Protein 1 (RALBP1))

Autre désignation: RALBP1

Sujet: RALBP1 can activate specifically hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. RALBP1 mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes.RALBP1 can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. RALBP1 serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDK1 to switch off endocytosis, One of its substrates would be EPN1/Epsin.
Alias Symbols: RIP, RIP1, RLIP76, RLIP1
Protein Interaction Partner: TNIP1, CEP57, SMARCE1, PPL, GPS2, GSE1, ZNF707, ZBTB38, C1orf216, TBRG1, AMOTL2, TFPT, UBC, RALB, GPSM1, PRKCA, CPSF2, POLR2A, AP2A1, SYNJ2BP, HOOK2, REPS1, FADD, RAC1, TRAF2, CASP8, AP2M1, REPS2, IKBKG, RALA, CCNB1, HSP90AA1, HSF1, EPN1, NUMB, GTF3A, TNF
Protein Size: 655

Poids moléculaire: 76 kDa

ID gène: 10928

NCBI Accession: NM_006788, NP_006779

UniProt: Q15311