KATNA1 anticorps (C-Term)

N° du produit ABIN2784857

Cet anticorps Lapin Polyclonal détecte spécifiquement KATNA1 dans WB. Il présente une réactivité envers Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin et Poisson zèbre (Danio rerio).

Aperçu rapide pour KATNA1 anticorps (C-Term) (ABIN2784857)

Antigène: KATNA1 (Katanin P60 (ATPase Containing) Subunit A 1 (KATNA1))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KATNA1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-KATNA1 anticorps

Épitope: C-Term

Séquence: DDPSKMVMVL AATNFPWDID EALRRRLEKR IYIPLPSAKG REELLRISLR

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

Attributs du produit: This is a rabbit polyclonal antibody against Katna1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide corresponding to a region of Mouse

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 491 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur KATNA1

Antigène: KATNA1 (Katanin P60 (ATPase Containing) Subunit A 1 (KATNA1))

Autre désignation: Katna1

Sujet: Katna1 severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays, such as that seen during disassembly of interphase microtubules at the G2-M transition.It may also be required for microtubule release from the centrosome after nucleation. In mitotic spindles this could allow depolymerization of the microtubule end proximal to the centrosome, and subsequent poleward microtubule flux. In neurons, microtubule release within the cell body allows their subsequent transport into neuronal processes by microtubule dependent motor proteins. This transport is required for axonal growth.
Alias Symbols: -
Protein Interaction Partner: KATNB1,
Protein Size: 491

Poids moléculaire: 54 kDa

ID gène: 23924

NCBI Accession: NM_011835, NP_035965

UniProt: Q9WV86

Pathways: Dynamique des Microtubules