KATNA1 anticorps (C-Term)
Aperçu rapide pour KATNA1 anticorps (C-Term) (ABIN2784857)
Antigène
Voir toutes KATNA1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Fonction
- Katna1 Antibody - C-terminal region
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Séquence
- DDPSKMVMVL AATNFPWDID EALRRRLEKR IYIPLPSAKG REELLRISLR
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%
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Attributs du produit
- This is a rabbit polyclonal antibody against Katna1. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide corresponding to a region of Mouse
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP52277-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- KATNA1 (Katanin P60 (ATPase Containing) Subunit A 1 (KATNA1))
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Autre désignation
- Katna1
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Sujet
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Targeted Subunit: A1
Background Information: Katna1 severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays, such as that seen during disassembly of interphase microtubules at the G2-M transition.It may also be required for microtubule release from the centrosome after nucleation. In mitotic spindles this could allow depolymerization of the microtubule end proximal to the centrosome, and subsequent poleward microtubule flux. In neurons, microtubule release within the cell body allows their subsequent transport into neuronal processes by microtubule dependent motor proteins. This transport is required for axonal growth.
Gene Name: Katanin p60 (ATPase-containing) subunit A1
Alternative Symbols: -
Protein Name: Katanin p60 ATPase-containing subunit A1
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Poids moléculaire
- 54kDa
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ID gène
- 23924
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NCBI Accession
- NP_035965
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UniProt
- Q9WV86
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Pathways
- Dynamique des Microtubules
Antigène
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