EXOC3 anticorps (Middle Region)
Aperçu rapide pour EXOC3 anticorps (Middle Region) (ABIN2784880)
Antigène
Voir toutes EXOC3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Séquence
- LERTVTTRIE GTQADTRESD KMWLVRHLEI IRKYVLDDLI VAKNLMVQCF
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
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Attributs du produit
- This is a rabbit polyclonal antibody against EXOC3. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human EXOC3
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 745 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- EXOC3 (Exocyst Complex Component 3 (EXOC3))
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Autre désignation
- EXOC3
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Sujet
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EXOC3 is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity.The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity.
Alias Symbols: SEC6, SEC6L1, Sec6p
Protein Interaction Partner: UBC, INPP5K, PRPF19, KIAA0907, EGFR, EXOC4, BUB3, MLH1, EXOC8, EXOC2, EXOC6, EXOC5, APP, MYO5A, Poc1b, RALA, GRIN2B, DLG3,
Protein Size: 745 -
Poids moléculaire
- 85 kDa
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ID gène
- 11336
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NCBI Accession
- NM_007277, NP_009208
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UniProt
- Q6P2E8
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Pathways
- Peptide Hormone Metabolism, Synaptic Vesicle Exocytosis
Antigène
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