Dynamin 1-Like anticorps (N-Term)

N° du produit ABIN2784887

Détail du produit anti-Dynamin 1-Like anticorps

Antigène: Dynamin 1-Like (DNM1L)

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Lapin, Cobaye, Cheval, Saccharomyces cerevisiae, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Dynamin 1-Like est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: IRQEIENETE RISGNNKGVS PEPIHLKIFS PNVVNLTLVD LPGMTKVPVG

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 85%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against DNM1L. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human DNM1L

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 736 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-Dynamin 1-Like (ABIN2784887)

Su, Chiu, Hung, Hong: "Beta-nodavirus B2 protein induces hydrogen peroxide production, leading to Drp1-recruited mitochondrial fragmentation and cell death via mitochondrial targeting." dans: Apoptosis : an international journal on programmed cell death, Vol. 19, Issue 10, pp. 1457-70, (2014) (PubMed).

Détails sur Dynamin 1-Like

Antigène: Dynamin 1-Like (DNM1L)

Autre désignation: DNM1L (DNM1L Produits)

Synonymes: anticorps DLP1, anticorps DRP1, anticorps DVLP, anticorps DYMPLE, anticorps EMPF, anticorps HDYNIV, anticorps 6330417M19Rik, anticorps AI450666, anticorps Dlp1, anticorps Dnmlp1, anticorps Drp1, anticorps python, anticorps Dnml1, anticorps dnm1l, anticorps MGC53850, anticorps zgc:66163, anticorps DNM1L, anticorps 18.m06247, anticorps CG3210, anticorps DRP, anticorps Dmel\CG3210, anticorps Dnm1/Drp1, anticorps Drp, anticorps Drp-1, anticorps drp-1, anticorps drp1, anticorps frat, anticorps l(2)22Fc, anticorps l(2)22Fd, anticorps l(2)ND2, anticorps l(2)ND3, anticorps dynamin 1 like, anticorps dynamin 1-like, anticorps dynamin 1-like L homeolog, anticorps dynamin-1-like, anticorps dynamin-1-like protein, anticorps dynamin-like protein, anticorps Dynamin related protein 1, anticorps DNM1L, anticorps Dnm1l, anticorps dnm1l.L, anticorps dnm1l, anticorps LOC100369408, anticorps LOC411472, anticorps dyn1, anticorps cgd1_580, anticorps EHI_052740, anticorps PVX_092875, anticorps BBOV_II002980, anticorps Drp1

Sujet: The protein encoded by this gene is a member of the dynamin superfamily of GTPases. Members of the dynamin-related subfamily, including the S. cerevisiae proteins Dnm1 and Vps1, contain the N-terminal tripartite GTPase domain but do not have the pleckstrin homology or proline-rich domains. This protein establishes mitochondrial morphology through a role in distributing mitochondrial tubules throughout the cytoplasm. The gene has 3 alternatively spliced transcripts encoding different isoforms. These transcripts are alternatively polyadenylated.
Alias Symbols: DLP1, DRP1, DVLP, DYMPLE, HDYNIV, VPS1, EMPF, DYNIV-11
Protein Interaction Partner: ZBTB24, UBC, SCG3, SH3GL1, RRM2, MAGEA3, MAGEA1, MARCH5, EGFR, VPS26A, SSB, CARS, ATP6V1C1, APEH, PSMG3, FAM129B, TBC1D15, CYHR1, ARFIP1, JMJD6, SEC24A, SOX2, DNM1L, MIEF2, MFF, PEX14, LRRK2, MIEF1, COPS5, GABRR1, MUL1, SUMO2, PARK2, PEX25, PEX11G, PEX11A
Protein Size: 736

Poids moléculaire: 82 kDa

ID gène: 10059

NCBI Accession: NM_012062, NP_036192

UniProt: O00429