CSH1 anticorps (Middle Region)

N° du produit ABIN2784912

Détail du produit anti-CSH1 anticorps

Antigène: CSH1 (Chorionic Somatomammotropin Hormone 1 (Placental Lactogen) (CSH1))

Épitope: Middle Region

Reactivité: Humain, Souris, Chien, Cobaye, Lapin, Rat, Boeuf (Vache), Chévre, Cheval, Porc, Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CSH1 est non-conjugé

Application: Western Blotting (WB)

Séquence: LFDHAMLQAH RAHQLAIDTY QEFRLEDGSR RTGQILKQTY SKFDTNSHNH

Homologie: Cow: 79%, Dog: 86%, Goat: 90%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 86%, Pig: 86%, Rabbit: 79%, Rat: 86%, Sheep: 90%

Attributs du produit: This is a rabbit polyclonal antibody against CSH2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human CSH2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 122 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CSH1

Antigène: CSH1 (Chorionic Somatomammotropin Hormone 1 (Placental Lactogen) (CSH1))

Autre désignation: CSH2 (CSH1 Produits)

Synonymes: anticorps CS-1, anticorps CSA, anticorps CSMT, anticorps PL, anticorps hCS-A, anticorps CS-2, anticorps CSB, anticorps hCS-B, anticorps chorionic somatomammotropin hormone 1, anticorps chorionic somatomammotropin hormone 2, anticorps CSH1, anticorps CSH2

Sujet: The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones and plays an important role in growth control. The gene is located at the growth hormone locus on chromosome 17 along with four other related genes in the same transcriptional orientation, an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. Alternative splicing generates additional isoforms of each of the five growth hormones. This particular family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites. Expression of the identical mature proteins for chorionic somatomammotropin hormones 1 and 2 is upregulated during development, while the ratio of 1 to 2 increases by term. Structural and expression differences provide avenues for developmental regulation and tissue specificity.
Alias Symbols: CS-2, CSB, hCS-B
Protein Interaction Partner: PTPN12, SMAD9, SMAD4, SMAD3, SMAD2, POLR2A,
Protein Size: 122

Poids moléculaire: 14 kDa

ID gène: 1443

NCBI Accession: NM_022645, NP_072171

UniProt: B1A4H9

Pathways: Response to Growth Hormone Stimulus