TRAF3IP2 anticorps (N-Term)

N° du produit ABIN2785129

L’anticorps Lapin Polyclonal anti-TRAF3IP2 a été validé pour WB. Il convient pour détecter TRAF3IP2 dans des échantillons de Humain, Rat, Souris, Cobaye et Cheval.

Aperçu rapide pour TRAF3IP2 anticorps (N-Term) (ABIN2785129)

Antigène: TRAF3IP2 (TRAF3 Interacting Protein 2 (TRAF3IP2))

Reactivité: Humain, Rat, Souris, Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRAF3IP2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-TRAF3IP2 anticorps

Épitope: N-Term

Séquence: IPVEVDESEP YPSQLLKPIP EYSPEEESEP PAPNIRNMAP NSLSAPTMLH

Homologie: Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rat: 86%

Attributs du produit: This is a rabbit polyclonal antibody against TRAF3IP2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human TRAF3IP2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 574 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur TRAF3IP2

Antigène: TRAF3IP2 (TRAF3 Interacting Protein 2 (TRAF3IP2))

Autre désignation: TRAF3IP2

Sujet: This gene encodes a protein involved in regulating responses to cytokines by members of the Rel/NF-kappaB transcription factor family. These factors play a central role in innate immunity in response to pathogens, inflammatory signals and stress. This gene product interacts with TRAF proteins (tumor necrosis factor receptor-associated factors) and either I-kappaB kinase or MAP kinase to activate either NF-kappaB or Jun kinase. Several alternative transcripts encoding different isoforms have been identified. Another transcript, which does not encode a protein and is transcribed in the opposite orientation, has been identified. Overexpression of this transcript has been shown to reduce expression of at least one of the protein encoding transcripts, suggesting it has a regulatory role in the expression of this gene.
Alias Symbols: ACT1, C6orf2, C6orf4, C6orf5, C6orf6, CIKS, DKFZp586G0522, MGC3581, PSORS13
Protein Interaction Partner: RIMBP3, IL17RA, MRPL28, STK16, UBE2V1, TRIP6, TRAF6, SYK, SRSF1, FHL3, ELAVL1, TRAF2, FBXW11, BTRC, UBC, Dlg4, TBK1, IKBKE, TNFRSF13C, TRAF3, CD40, MAP3K7, TRAF3IP2, IKBKG, IKBKB, CHUK, IL17A, MDFI, TRAF5, TRAF1,
Protein Size: 574

Poids moléculaire: 65 kDa

ID gène: 10758

NCBI Accession: NM_147200, NP_671733

UniProt: O43734

Pathways: Production of Molecular Mediator of Immune Response