Nesprin3 anticorps (N-Term)

N° du produit ABIN2785211

Détail du produit anti-Nesprin3 anticorps

Antigène: Nesprin3 (C14orf49) (Chromosome 14 Open Reading Frame 49 (C14orf49))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Cheval, Porc, Chien, Boeuf (Vache), Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Nesprin3 est non-conjugé

Application: Western Blotting (WB)

Séquence: AQVLLHNVDN QAVLLDRLLE EAASLFNRIG DPSVDEDAQK RMKAEYDAVK

Homologie: Cow: 93%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against SYNE3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human SYNE3

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Nesprin3

Antigène: Nesprin3 (C14orf49) (Chromosome 14 Open Reading Frame 49 (C14orf49))

Autre désignation: SYNE3 (C14orf49 Produits)

Synonymes: anticorps C14orf49, anticorps NET53, anticorps Nesp3, anticorps 4831426I19Rik, anticorps nesprin-3, anticorps spectrin repeat containing nuclear envelope family member 3, anticorps spectrin repeat containing, nuclear envelope family member 3, anticorps SYNE3, anticorps Syne3

Sujet: SYNE3 is a component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. It is involved in the maintenance of nuclear organization and structural integrity. It is a probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system. SYNE3 plays a role in the regulation of aortic epithelial cell morphology, and is required for flow-induced centrosome polarization and directional migration in aortic endothelial cells.
Protein Size: 596

Poids moléculaire: 65 kDa

ID gène: 161176

Pathways: Maintenance of Protein Location