Nesprin3 anticorps (N-Term)

N° du produit ABIN2785211

Cet anticorps Lapin Polyclonal détecte spécifiquement Nesprin3 dans WB. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Chien, Cheval, Porc, Boeuf (Vache) et Lapin.

Aperçu rapide pour Nesprin3 anticorps (N-Term) (ABIN2785211)

Antigène: Nesprin3 (C14orf49) (Chromosome 14 Open Reading Frame 49 (C14orf49))

Reactivité: Humain, Souris, Rat, Chien, Cheval, Porc, Boeuf (Vache), Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Nesprin3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Nesprin3 anticorps

Épitope: N-Term

Fonction: SYNE3 Antibody - N-terminal region

Séquence: AQVLLHNVDN QAVLLDRLLE EAASLFNRIG DPSVDEDAQK RMKAEYDAVK

Homologie: Cow: 93%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against SYNE3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human SYNE3

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP53053-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur Nesprin3

Antigène: Nesprin3 (C14orf49) (Chromosome 14 Open Reading Frame 49 (C14orf49))

Autre désignation: SYNE3

Sujet:

Background Information: SYNE3 is a component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. It is involved in the maintenance of nuclear organization and structural integrity. It is a probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system. SYNE3 plays a role in the regulation of aortic epithelial cell morphology, and is required for flow-induced centrosome polarization and directional migration in aortic endothelial cells.

Gene Name: spectrin repeat containing, nuclear envelope family member 3

Alternative Symbols: KASH3, NET53, Nesp3, C14orf49, C14orf139, LINC00341, NCRNA00341

Protein Name: Nesprin-3

Poids moléculaire: 65kDa

ID gène: 161176

UniProt: Q6ZMZ3

Pathways: Maintenance of Protein Location