TTL anticorps (Middle Region)

N° du produit ABIN2785284

L’anticorps anti-TTL Polyclonal Lapin est utilisé pour la détection de TTL dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin et Poisson zèbre (Danio rerio). Il a été validé pour WB.

Aperçu rapide pour TTL anticorps (Middle Region) (ABIN2785284)

Antigène: TTL (Tubulin tyrosine Ligase (TTL))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TTL est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-TTL anticorps

Épitope: Middle Region

Fonction: TTL Antibody - middle region

Séquence: LYREGVLRTA SEPYHVDNFQ DKTCHLTNHC IQKEYSKNYG KYEEGNEMFF

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against TTL. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human TTL

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP53199-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur TTL

Antigène: TTL (Tubulin tyrosine Ligase (TTL))

Autre désignation: TTL

Sujet:

Background Information: TTL catalyzes the post-translational addition of a tyrosine to the C-terminal end of detyrosinated alpha-tubulin.TTL is a cytosolic enzyme involved in the posttranslational modification of alpha-tubulin (see MIM 602529). Alpha-tubulin within assembled microtubules is detyrosinated over time at the C terminus. After microtubule disassembly, TTL restores the tyrosine residues and consequently participates in a cycle of tubulin detyrosination and tyrosination (Erck et al., 2003 [PubMed 14571137]).[supplied by OMIM].

Gene Name: Tubulin tyrosine ligase

Alternative Symbols: MGC46235

Protein Name: Tubulin--tyrosine ligase

Poids moléculaire: 43kDa

ID gène: 150465

NCBI Accession: NP_714923

UniProt: Q8NG68

Pathways: Regulation of Cell Size