CCDC50 anticorps (Middle Region)
Aperçu rapide pour CCDC50 anticorps (Middle Region) (ABIN2785358)
Antigène
Voir toutes CCDC50 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Fonction
- CCDC50 Antibody - middle region
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Séquence
- GMKPRVMKEA VSTPSRMAHR DQEWYDAEIA RKLQEEELLA TQVDMRAAQV
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 77%
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Attributs du produit
- This is a rabbit polyclonal antibody against CCDC50. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human CCDC50
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8097702
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- CCDC50 (Coiled-Coil Domain Containing 50 (CCDC50))
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Autre désignation
- CCDC50
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Sujet
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Background Information: CCDC50 is a soluble, cytoplasmic, tyrosine-phosphorylated protein with multiple ubiquitin-interacting domains. Mutations in this gene cause nonsyndromic, postlingual, progressive sensorineural DFNA44 hearing loss. In mouse, the protein is expressed in the inner ear during development and postnatal maturation and associates with microtubule-based structures. This protein may also function as a negative regulator of NF-kB signaling and as an effector of epidermal growth factor (EGF)-mediated cell signaling.
Gene Name: Coiled-coil domain containing 50
Alternative Symbols: YMER, C3orf6, DFNA44
Protein Name: Coiled-coil domain-containing protein 50
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Poids moléculaire
- 56kDa
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ID gène
- 152137
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NCBI Accession
- NP_848018
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UniProt
- Q8IVM0
Antigène
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