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LRRC50 anticorps (N-Term)

Cet anticorps Lapin Polyclonal détecte spécifiquement LRRC50 dans WB. Il présente une réactivité envers Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval et Poisson zèbre (Danio rerio) et a été mentionné dans 3+ publications.
N° du produit ABIN2785360

Aperçu rapide pour LRRC50 anticorps (N-Term) (ABIN2785360)

Antigène

Voir toutes LRRC50 Anticorps
LRRC50 (Leucine Rich Repeat Containing 50 (LRRC50))

Reactivité

  • 10
  • 5
  • 5
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval, Poisson zèbre (Danio rerio)

Hôte

  • 6
  • 4
Lapin

Clonalité

  • 6
  • 4
Polyclonal

Conjugué

  • 10
Cet anticorp LRRC50 est non-conjugé

Application

  • 9
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Épitope

    • 2
    • 1
    • 1
    • 1
    N-Term

    Séquence

    LNDTLYLHFK GFDRIENLEE YTGLRCLWLQ SNGIQKIENL EAQTELRCLF

    Homologie

    Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 79%

    Attributs du produit

    This is a rabbit polyclonal antibody against LRRC50. It was validated on Western Blot using a cell lysate as a positive control.

    Purification

    Affinity Purified

    Immunogène

    The immunogen is a synthetic peptide directed towards the N terminal region of human LRRC50
  • Indications d'application

    Optimal working dilutions should be determined experimentally by the investigator.

    Commentaires

    Antigen size: 725 AA

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freeze-thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Basten, Davis, Gillis, van Rooijen, Stoop, Babala, Logister, Heath, Jonges, Katsanis, Voest, van Eeden, Medema, Ketting, Schulte-Merker, Looijenga, Giles: "Mutations in LRRC50 predispose zebrafish and humans to seminomas." dans: PLoS genetics, Vol. 9, Issue 4, pp. e1003384, (2013) (PubMed).

    Yang, Zhou, Ma, Wang, Chen, Meng, Yu, Zhou, Sun: "Knockdown of PPAR δ gene promotes the growth of colon cancer and reduces the sensitivity to bevacizumab in nude mice model." dans: PLoS ONE, Vol. 8, Issue 4, pp. e60715, (2013) (PubMed).

    Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." dans: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).

  • Antigène

    LRRC50 (Leucine Rich Repeat Containing 50 (LRRC50))

    Autre désignation

    LRRC50

    Sujet

    LRRC50 contains 6 LRR (leucine-rich) repeats. It is proposed that LRRC50 to be a novel candidate gene for human cystic kidney disease, involved in regulation of microtubule-based cilia and actin-based brush border microvilli.
    Alias Symbols: DKFZp434A119, FLJ25330, ODA7, CILD13, LRRC50
    Protein Interaction Partner: UBC,
    Protein Size: 725

    Poids moléculaire

    80 kDa

    ID gène

    123872

    NCBI Accession

    NM_178452, NP_848547

    UniProt

    Q8NEP3
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