IL-24 anticorps (C-Term)
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- Antigène Voir toutes IL-24 (IL24) Anticorps
- IL-24 (IL24) (Interleukin 24 (IL24))
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Épitope
- C-Term
- Reactivité
- Humain, Rat, Souris, Chien, Cheval
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp IL-24 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- STLANNFVLI VSQLQPSQEN EMFSIRDSAH RRFLLFRRAF KQLDVEAALT
- Homologie
- Dog: 77%, Horse: 85%, Human: 100%, Mouse: 85%, Rat: 85%
- Attributs du produit
- This is a rabbit polyclonal antibody against IL24. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C-terminal region of IL24
- Top Product
- Discover our top product IL24 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 207 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- IL-24 (IL24) (Interleukin 24 (IL24))
- Autre désignation
- IL24 (IL24 Produits)
- Synonymes
- anticorps C49A, anticorps FISP, anticorps IL10B, anticorps MDA7, anticorps MOB5, anticorps ST16, anticorps Mda7, anticorps St16, anticorps Mda-7, anticorps IL24, anticorps interleukin 24, anticorps IL24, anticorps Il24
- Sujet
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This gene encodes a member of the IL10 family of cytokines. It was identified as a gene induced during terminal differentiation in melanoma cells. The protein encoded by this gene can induce apoptosis selectively in various cancer cells. Overexpression of this gene leads to elevated expression of several GADD family genes, which correlates with the induction of apoptosis. The phosphorylation of mitogen-activated protein kinase 14 (MAPK7/P38), and heat shock 27 kDa protein 1 (HSPB2/HSP27) are found to be induced by this gene in melanoma cells, but not in normal immortal melanocytes. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Alias Symbols: C49A, FISP, IL-24, IL10B, MDA7, Mob-5, ST16, mda-7, MOB5
Protein Interaction Partner: DCD, RARG, CCR5, CLU, UBC, IL20RA,
Protein Size: 207 - Poids moléculaire
- 22 kDa
- ID gène
- 11009
- NCBI Accession
- NM_001185156, NP_001172085
- UniProt
- Q53XZ7
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Autophagy
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