IL-24 anticorps (C-Term)

N° du produit ABIN2785371

Cet anticorps anti-IL-24 Polyclonal Lapin (ABIN2785371) détecte spécifiquement IL-24 dans WB. L’anticorps est réactif avec des échantillons de Humain, Rat, Souris, Chien et Cheval.

Aperçu rapide pour IL-24 anticorps (C-Term) (ABIN2785371)

Antigène: IL-24 (IL24) (Interleukin 24 (IL24))

Reactivité: Humain, Rat, Souris, Chien, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL-24 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-IL-24 anticorps

Épitope: C-Term

Fonction: IL24 Antibody - C-terminal region

Séquence: STLANNFVLI VSQLQPSQEN EMFSIRDSAH RRFLLFRRAF KQLDVEAALT

Homologie: Dog: 77%, Horse: 85%, Human: 100%, Mouse: 85%, Rat: 85%

Attributs du produit: This is a rabbit polyclonal antibody against IL24. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of IL24

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP53387-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur IL-24

Antigène: IL-24 (IL24) (Interleukin 24 (IL24))

Autre désignation: IL24

Sujet:

Background Information: This gene encodes a member of the IL10 family of cytokines. It was identified as a gene induced during terminal differentiation in melanoma cells. The protein encoded by this gene can induce apoptosis selectively in various cancer cells. Overexpression of this gene leads to elevated expression of several GADD family genes, which correlates with the induction of apoptosis. The phosphorylation of mitogen-activated protein kinase 14 (MAPK7/P38), and heat shock 27 kDa protein 1 (HSPB2/HSP27) are found to be induced by this gene in melanoma cells, but not in normal immortal melanocytes. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Alternative Symbols: C49A, FISP, MDA7, MOB5, ST16, IL10B

Protein Name: Interleukin-24

Poids moléculaire: 22kDa

ID gène: 11009

NCBI Accession: NP_001172085

UniProt: Q53XZ7

Pathways: Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Autophagy