IL-24 anticorps (AA 52-140)

N° du produit ABIN6142368

Détail du produit anti-IL-24 anticorps

Antigène: IL-24 (IL24) (Interleukin 24 (IL24))

Épitope: AA 52-140

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL-24 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: GQEFHFGPCQ VKGVVPQKLW EAFWAVKDTM QAQDNITSAR LLQQEVLQNV SDAESCYLVH TLLEFYLKTV FKNYHNRTVE VRTLKSFST

Réactivité croisée: Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 52-140 of human IL24 (NP_001172085.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur IL-24

Antigène: IL-24 (IL24) (Interleukin 24 (IL24))

Autre désignation: IL24 (IL24 Produits)

Synonymes: anticorps C49A, anticorps FISP, anticorps IL10B, anticorps MDA7, anticorps MOB5, anticorps ST16, anticorps Mda7, anticorps St16, anticorps Mda-7, anticorps IL24, anticorps interleukin 24, anticorps IL24, anticorps Il24

Sujet: This gene encodes a member of the IL10 family of cytokines. It was identified as a gene induced during terminal differentiation in melanoma cells. The protein encoded by this gene can induce apoptosis selectively in various cancer cells. Overexpression of this gene leads to elevated expression of several GADD family genes, which correlates with the induction of apoptosis. The phosphorylation of mitogen-activated protein kinase 14 (MAPK7/P38), and heat shock 27 kDa protein 1 (HSPB2/HSP27) are found to be induced by this gene in melanoma cells, but not in normal immortal melanocytes. Alternatively spliced transcript variants encoding distinct isoforms have been reported.,IL24,C49A,FISP,IL10B,MDA7,MOB5,ST16,Cancer,Tumor immunology,Cell Biology & Developmental Biology,Apoptosis,Immunology & Inflammation,Cytokines,Interleukins,Cell Intrinsic Innate Immunity Signaling Pathway,IL24

Poids moléculaire: 7 kDa/17 kDa/23 kDa

ID gène: 11009

UniProt: Q13007

Pathways: Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Autophagy