Importin 5 anticorps (N-Term)

N° du produit ABIN2785469

L’anticorps anti-Importin 5 Polyclonal Lapin est utilisé pour la détection de Importin 5 dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin et Poisson zèbre (Danio rerio). Il a été validé pour WB.

Aperçu rapide pour Importin 5 anticorps (N-Term) (ABIN2785469)

Antigène: Importin 5 (IPO5)

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Importin 5 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Importin 5 anticorps

Épitope: N-Term

Fonction: RANBP5 Antibody - N-terminal region

Séquence: GNNQWPEGLK FLFDSVSSQN VGLREAALHI FWNFPGIFGN QQQHYLDVIK

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against RANBP5. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human RANBP5

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP53600-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur Importin 5

Antigène: Importin 5 (IPO5)

Autre désignation: RANBP5

Sujet:

Background Information: Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family.

Gene Name: Importin 5

Alternative Symbols: IMB3, Pse1, imp5, KPNB3, RANBP5

Protein Name: Importin-5

Poids moléculaire: 125kDa

ID gène: 3843

NCBI Accession: NP_002262

UniProt: O00410

Pathways: Protein targeting to Nucleus