TUBA3C anticorps (N-Term)

N° du produit ABIN2785497

Détail du produit anti-TUBA3C anticorps

Antigène: TUBA3C (Tubulin, Alpha, 3C (TUBA3C))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Porc, Lapin, Poisson zèbre (Danio rerio), Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TUBA3C est non-conjugé

Application: Western Blotting (WB)

Séquence: QMPSDKTIGG GDDSFNTFFS ETGAGKHVPR AVFVDLEPTV VDEVRTGTYR

Homologie: Cow: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against TUBA3C. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human TUBA3C

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 450 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur TUBA3C

Antigène: TUBA3C (Tubulin, Alpha, 3C (TUBA3C))

Autre désignation: TUBA3C (TUBA3C Produits)

Sujet: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain.Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulin. The genes encoding these microtubule constituents are part of the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes and they are highly conserved among and between species. This gene is an alpha tubulin gene that encodes a protein 99 % identical to the mouse testis-specific Tuba3 and Tuba7 gene products. This gene is located in the 13q11 region, which is associated with the genetic diseases Clouston hidrotic ectodermal dysplasia and Kabuki syndrome. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: TUBA2, bA408E5.3, TUBA3D
Protein Interaction Partner: CEP70, UBC, MDM2, CD81, K3, UBL4A, DYNLT1, TSGA10, CUL3, ARRB2, ARRB1, VHL, YWHAQ, DYRK2, YWHAZ, YWHAG, YWHAB, PPP4C, PFDN5, GRM7, NMI, PXN, SIAH1, DYNLL1, TUBG1, MYC, FYN, FBL,
Protein Size: 450

Poids moléculaire: 50 kDa

ID gène: 7278

NCBI Accession: NM_006001, NP_005992

UniProt: Q13748

Pathways: Dynamique des Microtubules