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SPAG6 anticorps (Middle Region)

SPAG6 Reactivité: Humain, Souris, Rat, Porc, Lapin, Boeuf (Vache), Chien, Cheval, Poisson zèbre (Danio rerio), Cobaye WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2785513
  • Antigène Voir toutes SPAG6 Anticorps
    SPAG6 (Sperm Associated Antigen 6 (SPAG6))
    Épitope
    • 15
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Middle Region
    Reactivité
    • 24
    • 23
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat, Porc, Lapin, Boeuf (Vache), Chien, Cheval, Poisson zèbre (Danio rerio), Cobaye
    Hôte
    • 35
    • 4
    Lapin
    Clonalité
    • 36
    • 3
    Polyclonal
    Conjugué
    • 16
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SPAG6 est non-conjugé
    Application
    • 27
    • 13
    • 13
    • 11
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    HVVGQFSKVL PHDSKARRLF VTSGGLKKVQ EIKAEPGSLL QEYINSINSC
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against SPAG6. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the middle region of human SPAG6
    Top Product
    Discover our top product SPAG6 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 509 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Mehrle, Rosenfelder, Schupp, del Val, Arlt, Hahne, Bechtel, Simpson, Hofmann, Hide, Glatting, Huber, Pepperkok, Poustka, Wiemann: "The LIFEdb database in 2006." dans: Nucleic acids research, Vol. 34, Issue Database issue, pp. D415-8, (2005) (PubMed).

  • Antigène
    SPAG6 (Sperm Associated Antigen 6 (SPAG6))
    Autre désignation
    SPAG6 (SPAG6 Produits)
    Synonymes
    anticorps Repro-SA-1, anticorps pf16, anticorps PF16, anticorps RGD1310892, anticorps zgc:91805, anticorps SPAG6, anticorps repro-sa-1, anticorps DKFZp459D035, anticorps sperm associated antigen 6, anticorps sperm associated antigen 6-like, anticorps sperm associated antigen 6 L homeolog, anticorps SPAG6, anticorps Spag6l, anticorps Spag6, anticorps spag6, anticorps spag6.L
    Sujet
    SPAG6 is important for structural integrity of the central apparatus in the sperm tail and for flagellar motility.The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from an infertile man. This protein localizes to the tail of permeabilized human sperm and contains eight contiguous armadillo repeats, a motif known to mediate protein-protein interactions. Studies in mice suggest that this protein is involved in sperm flagellar motility and maintenance of the structural integrity of mature sperm. Alternatively spliced variants that encode different protein isoforms have been described but the full-length sequences of only two have been determined.
    Alias Symbols: DKFZp434I153, MGC26276, Repro-SA-1, pf16
    Protein Interaction Partner: APP, SPAG16,
    Protein Size: 509
    Poids moléculaire
    56 kDa
    ID gène
    9576
    NCBI Accession
    NM_012443, NP_036575
    UniProt
    O75602
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