SPA17 anticorps (N-Term)

N° du produit ABIN2785535

Cet anticorps Lapin Polyclonal détecte spécifiquement SPA17 dans WB. Il présente une réactivité envers Humain, Souris, Rat, Lapin, Cobaye, Cheval, Boeuf (Vache), Mouton, Chien, Porc et Poisson zèbre (Danio rerio).

Aperçu rapide pour SPA17 anticorps (N-Term) (ABIN2785535)

Antigène: SPA17 (Sperm Autoantigenic Protein 17 (SPA17))

Reactivité: Humain, Souris, Rat, Lapin, Cobaye, Cheval, Boeuf (Vache), Mouton, Chien, Porc, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SPA17 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SPA17 anticorps

Épitope: N-Term

Séquence: MSIPFSNTHY RIPQGFGNLL EGLTREILRE QPDNIPAFAA AYFESLLEKR

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against SPA17. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human SPA17

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 151 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SPA17

Antigène: SPA17 (Sperm Autoantigenic Protein 17 (SPA17))

Autre désignation: SPA17

Sujet: This gene encodes a protein present at the cell surface. The N-terminus has sequence similarity to human cAMP-dependent protein kinase A (PKA) type II alpha regulatory subunit (RIIa) while the C-terminus has an IQ calmodulin-binding motif. The central portion of the protein has carbohydrate binding motifs and likely functions in cell-cell adhesion. The protein was initially characterized by its involvement in the binding of sperm to the zona pellucida of the oocyte. Recent studies indicate that it is also involved in additional cell-cell adhesion functions such as immune cell migration and metastasis. A retrotransposed pseudogene is present on chromosome 10q22.
Alias Symbols: SP17, SP17-1, CT22
Protein Interaction Partner: MYL6B, ROPN1, AKAP7, UBC, ROPN1B, AKAP3,
Protein Size: 151

Poids moléculaire: 17 kDa

ID gène: 53340

NCBI Accession: NM_017425, NP_059121

UniProt: Q15506