ACAT1 anticorps (Middle Region)

N° du produit ABIN2785628

Détail du produit anti-ACAT1 anticorps

Antigène: ACAT1 (Acetyl-CoA Acetyltransferase 1 (ACAT1))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Lapin, Cheval, Cobaye, Poisson zèbre (Danio rerio), Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ACAT1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: GHQDVMVAGG MESMSNVPYV MNRGSTPYGG VKLEDLIVKD GLTDVYNKIH

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 92%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against ACAT1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human ACAT1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 427 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ACAT1

Antigène: ACAT1 (Acetyl-CoA Acetyltransferase 1 (ACAT1))

Autre désignation: ACAT1 (ACAT1 Produits)

Synonymes: anticorps ACAT, anticorps MAT, anticorps T2, anticorps THIL, anticorps RATACAL, anticorps 6330585C21Rik, anticorps Acat, anticorps fd16h07, anticorps fd20g06, anticorps wu:fd16h07, anticorps wu:fd20g06, anticorps zgc:86832, anticorps acat1-a, anticorps acetyl-CoA acetyltransferase 1, anticorps acetyl-Coenzyme A acetyltransferase 1, anticorps acetyl-CoA acetyltransferase 1 L homeolog, anticorps ACAT1, anticorps Acat1, anticorps acat1, anticorps acat1.L

Sujet: ACAT1 is a mitochondrially localized enzyme that catalyzes the reversible formation of acetoacetyl-CoA from two molecules of acetyl-CoA. The gene encoding ACAT1 spans approximately 27 kb and contains 12 exons interrupted by 11 introns. Defects in this gene are associated with the alpha-methylacetoaceticaciduria disorder, an inborn error of isoleucine catabolism characterized by urinary excretion of 2-methyl-3-hydroxybutyric acid, 2-methylacetoacetic acid, tiglylglycine, and butanone.
Alias Symbols: ACAT, MAT, T2, THIL
Protein Interaction Partner: SUMO2, MDM2, ACAT1, VCAM1, ITGA4, AGXT, FLOT1, UBAP2L, TTF2, UBL4A, UQCRFS1P1, UQCRB, SSBP1, SDHB, SDHA, SAFB, MARS, FOXM1, CSE1L, ACO2, TMEM65, TUBB1, TOMM7, TOPBP1, GCN1L1, TIMM44, ACAA2, FBXO6, PEX7, COPS5, CUL1, CUL3, SIRT7, SUMO1, RAD21, UBC, HDAC5,
Protein Size: 427

Poids moléculaire: 41 kDa

ID gène: 38

NCBI Accession: NM_000019, NP_000010

UniProt: P24752