FUCA1 anticorps (N-Term)

N° du produit ABIN2785639

Détail du produit anti-FUCA1 anticorps

Antigène: FUCA1 (Fucosidase, alpha-L- 1, Tissue (FUCA1))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Cobaye, Cheval, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FUCA1 est non-conjugé

Application: Western Blotting (WB)

Séquence: PSPVSWNWNS KDVGPHRDLV GELGTALRKR NIRYGLYHSL LEWFHPLYLL

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 79%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against FUCA1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human FUCA1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 466 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur FUCA1

Antigène: FUCA1 (Fucosidase, alpha-L- 1, Tissue (FUCA1))

Autre désignation: FUCA1 (FUCA1 Produits)

Synonymes: anticorps FUCA, anticorps FUCA1, anticorps 0610006A03Rik, anticorps 9530055J05Rik, anticorps Afuc, anticorps Fuca, anticorps fuca, anticorps fuca1, anticorps ATFUC1, anticorps F24D13.11, anticorps F24D13_11, anticorps alpha-L-fucosidase 1, anticorps wu:fb02a09, anticorps zgc:101116, anticorps alpha-L-fucosidase 1, anticorps fucosidase, alpha-L- 1, tissue, anticorps alpha-L-fucosidase 1 L homeolog, anticorps alpha-L-fucosidase 1, tandem duplicate 2, anticorps FUCA1, anticorps Fuca1, anticorps fuca1.L, anticorps fuca1, anticorps FUC1, anticorps LOC9317020, anticorps LOC100285202, anticorps fuca1.2

Sujet: Alpha-L-fucosidase (EC 3.2.1.51) is a lysosomal enzyme involved in the degradation of fucose-containing glycoproteins and glycolipids. At least 2 separate polymorphic alpha-L-fucosidases are recognized in man: that in tissues, FUCA1, which is deficient in fucosidosis, and that in plasma, FUCA2. Fucosidosis is an autosomal recessive lysosomal storage disease caused by defective alpha-L-fucosidase with accumulation of fucose in the tissues. Different phenotypes include clinical features such as neurologic deterioration, growth retardation, visceromegaly, and seizures in a severe early form, coarse facial features, angiokeratoma corporis diffusum, spasticity and delayed psychomotor development in a longer surviving form, and an unusual spondylometaphyseoepiphyseal dysplasia in yet another form.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FUCA
Protein Interaction Partner: PAXIP1, BARD1, APP, CUL3, VAV2, USP21, MARK2,
Protein Size: 466

Poids moléculaire: 54 kDa

ID gène: 2517

NCBI Accession: NM_000147, NP_000138

UniProt: P04066

Pathways: Glycosaminoglycan Metabolic Process