Glutathione Reductase anticorps (N-Term)

N° du produit ABIN2785662

Détail du produit anti-Glutathione Reductase anticorps

Antigène: Glutathione Reductase (GSR)

Épitope: N-Term

Reactivité: Humain, Rat, Souris, Lapin, Cobaye, Boeuf (Vache), Chien, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Glutathione Reductase est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: PTIEVSGKKY TAPHILIATG GMPSTPHESQ IPGASLGITS DGFFQLEELP

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against GSR. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human GSR

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 522 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-Glutathione Reductase (ABIN2785662)

Hoffmann, Dietrich, Herrmann, Schacht, Albrecht, Methner: "Dimethyl Fumarate Induces Glutathione Recycling by Upregulation of Glutathione Reductase." dans: Oxidative medicine and cellular longevity, Vol. 2017, pp. 6093903, (2017) (PubMed).

Détails sur Glutathione Reductase

Antigène: Glutathione Reductase (GSR)

Autre désignation: GSR (GSR Produits)

Synonymes: anticorps GR, anticorps ATGR2, anticorps EMB2360, anticorps glutathione reductase, anticorps AI325518, anticorps D8Ertd238e, anticorps Gr-1, anticorps Gr1, anticorps DDBDRAFT_0168952, anticorps DDBDRAFT_0231410, anticorps DDB_0168952, anticorps DDB_0231410, anticorps 2151, anticorps CG2151, anticorps DTR, anticorps Dm-TrxR, anticorps DmTR, anticorps DmTrx, anticorps DmTrxR, anticorps DmTrxR-1, anticorps Dmel\\CG2151, anticorps Gr, anticorps Trx, anticorps TrxR, anticorps TrxR-1, anticorps Trxr1, anticorps anon-WO03040301.185, anticorps anon-WO03040301.187, anticorps dTrxR, anticorps dmtrxr-1, anticorps gr, anticorps l(1)G0154, anticorps l(1)G0379, anticorps l(1)G0477, anticorps l(1)G0481, anticorps trxr-1, anticorps gor1, anticorps glutathione reductase, gro-2, anticorps glutathione reductase, anticorps glutathione-disulfide reductase, anticorps GR; GRase, anticorps mitochondrial glutathione reductase Pgr1, anticorps Glutathione reductase (GR) (GRase), anticorps Thioredoxin reductase-1, anticorps glutathione-disulfide reductase family protein, anticorps glutathione reductase 1, anticorps GR, anticorps gor, anticorps GSR, anticorps GSR1, anticorps Gsr_2, anticorps Gsr, anticorps GSHR1, anticorps gsr, anticorps LbGR, anticorps pgr1, anticorps GSHR2, anticorps GLR2, anticorps Bcen_2392, anticorps RPE_1989, anticorps HCAG_02219, anticorps SJAG_01162, anticorps Trxr-1, anticorps PF14_0192, anticorps POPTR_0001s14480g, anticorps gsr1

Sujet: GSR belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. It maintains high levels of reduced glutathione in the cytosol. Both glutathione and glutathione reductase are inducible by D3T, and that upregulation of GSH biosynthesis underlies D3T-mediated cytoprotection against ROS/RNS-elicited injury to human vascular smooth muscle cells.
Alias Symbols: MGC78522
Protein Interaction Partner: SUMO1, CNDP2, GINS2, PROSC, AHSA1, NDRG1, DDX39A, NAMPT, KYNU, DDX39B, RPS6KA1, PEPD, MVD, LDHA, HSPD1, GBP2, EEF2, ADSS, C11orf49, UBC, FOLR1, ISG15, ELAVL1, SUMO4, PJA1, OCM, GSR,
Protein Size: 522

Poids moléculaire: 56 kDa

ID gène: 2936

NCBI Accession: NM_000637, NP_000628

UniProt: P00390

Pathways: Thyroid Hormone Synthesis, Cell RedoxHomeostasis