Glutathione Reductase anticorps (N-Term)

N° du produit ABIN2785662

Il existe 1 publication pour ce produit. L’anticorps anti-Glutathione Reductase Polyclonal Lapin est utilisé pour la détection de Glutathione Reductase dans des échantillons de Humain, Souris, Rat, Lapin, Cobaye, Boeuf (Vache), Chien et Cheval. Il a été validé pour WB et IHC.

Aperçu rapide pour Glutathione Reductase anticorps (N-Term) (ABIN2785662)

Antigène: Glutathione Reductase (GSR)

Reactivité: Humain, Souris, Rat, Lapin, Cobaye, Boeuf (Vache), Chien, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Glutathione Reductase est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-Glutathione Reductase anticorps

Épitope: N-Term

Fonction: GSR Antibody - N-terminal region

Séquence: PTIEVSGKKY TAPHILIATG GMPSTPHESQ IPGASLGITS DGFFQLEELP

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against GSR. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human GSR

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP54344-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-Glutathione Reductase (ABIN2785662)

Hoffmann, Dietrich, Herrmann, Schacht, Albrecht, Methner: "Dimethyl Fumarate Induces Glutathione Recycling by Upregulation of Glutathione Reductase." dans: Oxidative medicine and cellular longevity, Vol. 2017, pp. 6093903, (2017) (PubMed).

Détails sur Glutathione Reductase

Antigène: Glutathione Reductase (GSR)

Autre désignation: GSR

Sujet:

Background Information: GSR belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. It maintains high levels of reduced glutathione in the cytosol. Both glutathione and glutathione reductase are inducible by D3T, and that upregulation of GSH biosynthesis underlies D3T-mediated cytoprotection against ROS/RNS-elicited injury to human vascular smooth muscle cells.

Gene Name: Glutathione reductase

Alternative Symbols: GR, GSRD, HEL-75, HEL-S-122m

Protein Name: Glutathione reductase, mitochondrial

Poids moléculaire: 56kDa

ID gène: 2936

NCBI Accession: NP_000628

UniProt: P00390

Pathways: Thyroid Hormone Synthesis, Cell RedoxHomeostasis