ALAS1 anticorps (N-Term)
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- Antigène Voir toutes ALAS1 Anticorps
- ALAS1 (Aminolevulinate, delta-, Synthase 1 (ALAS1))
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Épitope
- N-Term
- Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Mouton, Poisson zèbre (Danio rerio)
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ALAS1 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- ETSAGPSVVS VKTDGGDPSG LLKNFQDIMQ KQRPERVSHL LQDNLPKSVS
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 93%, Zebrafish: 86%
- Attributs du produit
- This is a rabbit polyclonal antibody against ALAS1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human ALAS1
- Top Product
- Discover our top product ALAS1 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 640 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- ALAS1 (Aminolevulinate, delta-, Synthase 1 (ALAS1))
- Autre désignation
- ALAS1 (ALAS1 Produits)
- Synonymes
- anticorps ALAS, anticorps ALAS3, anticorps ALASH, anticorps MIG4, anticorps ALAS-N, anticorps Alas-1, anticorps Alas-h, anticorps ALAS-H, anticorps ALASN, anticorps ALAS1, anticorps wu:fb58d01, anticorps wu:fi12g09, anticorps 5'-aminolevulinate synthase 1, anticorps aminolevulinic acid synthase 1, anticorps alanyl-tRNA synthetase protein, anticorps aminolevulinate, delta-, synthase 1, anticorps ALAS1, anticorps Alas1, anticorps alas1, anticorps alas1.S, anticorps alaS1
- Sujet
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Delta-aminolevulinate synthase (ALAS, EC 2.3.1.37) catalyzes the condensation of glycine with succinyl-CoA to form delta-aminolevulinic acid. This nuclear-encoded mitochondrial enzyme is the first and rate-limiting enzyme in the mammalian heme biosynthetic pathway. There are 2 tissue-specific isozymes: a housekeeping enzyme encoded by the ALAS1 gene and an erythroid tissue-specific enzyme encoded by ALAS2.
Alias Symbols: ALAS, ALAS3, ALASH, MIG4
Protein Interaction Partner: FAM127C, KLHL35, ZNF564, TEKT4, DUSP19, SNX20, MTFR2, LONRF1, ZMAT1, CDC73, TTC23, CERK, SH2D4A, EP400, C2orf42, GNL3L, CCHCR1, POLDIP2, ZFYVE26, USP20, TMSB10, ZNF175, WIPF1, UBC, TMSB4XP6, TMSB4XP2, TMSB4XP1, TMSB4X, TCEA2, PPL, BCL7A, ALAS1, PLAU, VHL,
Protein Size: 640 - Poids moléculaire
- 70 kDa
- ID gène
- 211
- NCBI Accession
- NM_000688, NP_000679
- UniProt
- P13196
- Pathways
- Regulation of Lipid Metabolism by PPARalpha
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