IMPDH1 anticorps (Middle Region)

N° du produit ABIN2785671

Détail du produit anti-IMPDH1 anticorps

Antigène: IMPDH1 (Inosine 5'-Phosphate Dehydrogenase 1 (IMPDH1))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Poisson zèbre (Danio rerio), Cobaye, Cheval, Lapin, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IMPDH1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: KKGKLPIVND CDELVAIIAR TDLKKNRDYP LASKDSQKQL LCGAAVGTRE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 79%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against IMPDH1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human IMPDH1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 563 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur IMPDH1

Antigène: IMPDH1 (Inosine 5'-Phosphate Dehydrogenase 1 (IMPDH1))

Autre désignation: IMPDH1 (IMPDH1 Produits)

Synonymes: anticorps IMPD, anticorps IMPD1, anticorps LCA11, anticorps RP10, anticorps sWSS2608, anticorps B930086D20Rik, anticorps IMPD 1, anticorps IMPDH 1, anticorps D3, anticorps IMPD 1b, anticorps IMPDH 1b, anticorps IMPDH1, anticorps id:ibd5035, anticorps si:dkey-31f5.7, anticorps wu:fa09h11, anticorps wu:fa99c03, anticorps zgc:113446, anticorps imp, anticorps imp1, anticorps imp2, anticorps IMPD 1a, anticorps IMPDH 1a, anticorps zgc:91911, anticorps inosine monophosphate dehydrogenase 1, anticorps inosine-5'-monophosphate dehydrogenase 1, anticorps IMP (inosine 5'-monophosphate) dehydrogenase 1b, anticorps IMP (inosine 5'-monophosphate) dehydrogenase 1, anticorps IMP (inosine 5'-monophosphate) dehydrogenase 1a, anticorps IMPDH1, anticorps Impdh1, anticorps LOC100442769, anticorps impdh1, anticorps impdh1b, anticorps impdh1.L, anticorps impdh1a

Sujet: IMPDH1 acts as a homotetramer to regulate cell growth. It is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10).
Alias Symbols: DKFZp781N0678, IMPD, IMPD1, LCA11, RP10, sWSS2608
Protein Interaction Partner: UBC, LAMP2, IMPDH2, XRCC6, GMNN, HTRA1, DDX3X, SUMO4,
Protein Size: 563

Poids moléculaire: 62 kDa

ID gène: 3614

NCBI Accession: NM_183243, NP_899066

UniProt: P20839

Pathways: Ribonucleoside Biosynthetic Process