Arylsulfatase A anticorps (N-Term)
Aperçu rapide pour Arylsulfatase A anticorps (N-Term) (ABIN2785757)
Antigène
Voir toutes Arylsulfatase A (ARSA) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- N-Term
-
Séquence
- DLGCYGHPSS TTPNLDQLAA GGLRFTDFYV PVSLCTPSRA ALLTGRLPVR
-
Homologie
- Cow: 100%, Dog: 92%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
-
Attributs du produit
- This is a rabbit polyclonal antibody against ARSA. It was validated on Western Blot using a cell lysate as a positive control.
-
Purification
- Affinity Purified
-
Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human ARSA
-
-
-
-
Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
-
Commentaires
-
Antigen size: 507 AA
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- Lot specific
-
Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
-
Stock
- -20 °C
-
Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- Arylsulfatase A (ARSA)
-
Autre désignation
- ARSA
-
Sujet
-
ARSA hydrolyzes cerebroside sulfate. Defects in ARSA are a cause of leukodystrophy metachromatic (MLD).The protein encoded by this gene hydrolyzes cerebroside sulfate to cerebroside and sulfate. Defects in this gene lead to metachromatic leucodystrophy (MLD), a progressive demyelination disease which results in a variety of neurological symptoms and ultimately death. Multiple alternatively spliced transcript variants, one of which encodes a distinct protein, have been described for this gene.
Alias Symbols: MLD
Protein Interaction Partner: TRIP13, PPIC, CETN2, CLEC4G, ARSA, GAL3ST1, BMPR2, CTSL,
Protein Size: 507 -
Poids moléculaire
- 56 kDa
-
ID gène
- 410
-
NCBI Accession
- NM_000487, NP_000478
-
UniProt
- P15289
Antigène
-