Pellino 3 anticorps (N-Term)
Aperçu rapide pour Pellino 3 anticorps (N-Term) (ABIN2785761)
Antigène
Voir toutes Pellino 3 (PELI3) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Fonction
- PELI3 Antibody - N-terminal region
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Séquence
- VLEGNPEVGS PRTSDLQHRG NKGSCVLSSP GEDAQPGEEP IKYGELIVLG
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Homologie
- Cow: 93%, Dog: 86%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 77%, Pig: 100%, Rabbit: 79%, Rat: 86%
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Attributs du produit
- This is a rabbit polyclonal antibody against PELI3. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human PELI3
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP54533-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- Pellino 3 (PELI3) (Pellino E3 Ubiquitin Protein Ligase Family Member 3 (PELI3))
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Autre désignation
- PELI3
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Sujet
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Background Information: Toll-like receptors (TLRs) and IL1R (IL1R1) are part of the innate immune response aimed at mobilizing defense mechanisms in response in infection or injury. Pellino proteins, such as PELI3, are intermediate components in the signaling cascades initiated by TLRs and IL1R.Toll-like receptors (TLRs, see MIM 603030) and IL1R (IL1R1, MIM 147810) are part of the innate immune response aimed at mobilizing defense mechanisms in response in infection or injury. Pellino proteins, such as PELI3, are intermediate components in the signaling cascades initiated by TLRs and IL1R (Jensen and Whitehead, 2003 [PubMed 12874243]).[supplied by OMIM].
Gene Name: Pellino E3 ubiquitin protein ligase family member 3
Alternative Symbols: MGC35521
Protein Name: E3 ubiquitin-protein ligase pellino homolog 3
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Poids moléculaire
- 48kDa
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ID gène
- 246330
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NCBI Accession
- NP_001091980
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UniProt
- Q8N2H9
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Pathways
- Toll-Like Receptors Cascades
Antigène
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