FKBP3 anticorps (C-Term)

N° du produit ABIN2785798

Cet anticorps Lapin Polyclonal détecte spécifiquement FKBP3 dans WB. Il présente une réactivité envers Humain, Souris, Rat, Boeuf (Vache), Cheval, Lapin, Chien, Cobaye et Poisson zèbre (Danio rerio).

Aperçu rapide pour FKBP3 anticorps (C-Term) (ABIN2785798)

Antigène: FKBP3 (FK506 Binding Protein 3, 25kDa (FKBP3))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cheval, Lapin, Chien, Cobaye, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FKBP3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-FKBP3 anticorps

Épitope: C-Term

Séquence: EALLTMSKGE KARLEIEPEW AYGKKGQPDA KIPPNAKLTF EVELVDID

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against FKBP3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human FKBP3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 224 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur FKBP3

Antigène: FKBP3 (FK506 Binding Protein 3, 25kDa (FKBP3))

Autre désignation: FKBP3

Sujet: FKBP3 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP3 is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.
Alias Symbols: FKBP-25, PPIase, FKBP-3, FKBP25
Protein Interaction Partner: UBC, EDC4, IGF2BP3, SYNCRIP, SEC16A, EIF2B2, EIF2B3, DYNLL1, RFC4, YBX1, NMT1, KRT18, ILF2, HNRNPU, HNRNPA2B1, DDX1, ABCF1, MAP1S, C14orf166, DIMT1, NELFB, SRPK1, FBXO25, BARD1, MYH10, PACSIN3, LRRFIP1, TIMELESS, Nedd4, NEDD4L, CALM1, HDAC2, HDAC1, YY1, C
Protein Size: 224

Poids moléculaire: 25 kDa

ID gène: 2287

NCBI Accession: NM_002013, NP_002004

UniProt: Q00688