FTH1 anticorps (N-Term)
Aperçu rapide pour FTH1 anticorps (N-Term) (ABIN2785802)
Antigène
Voir toutes FTH1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Séquence
- MTTASTSQVR QNYHQDSEAA INRQINLELY ASYVYLSMSY YFDRDDVALK
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Homologie
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against FTH1. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human FTH1
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 183 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- FTH1 (Ferritin, Heavy Polypeptide 1 (FTH1))
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Autre désignation
- FTH1
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Sujet
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FTH1 is the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases.
Alias Symbols: FTH, FTHL6, MGC104426, PIG15, PLIF, FHC
Protein Interaction Partner: SDCBP, FTL, FTH1, WDYHV1, CEP57, AURKB, TP53, AURKA, ASB15, ASB16, SUPT16H, SET, MAPK9, MAX, IGSF8, TICAM2, HCVgp1, PIAS4, CDC16, YWHAE, SOX5, MYL3, LBP, KPNA2, GRB2, DAXX, CSNK2B, CDC25A, ATP6V1B1, CD99, SPP1, TRAF4, SUMO2, UBC, Cep55, Trim28, NR1I3, NR3
Protein Size: 183 -
Poids moléculaire
- 21 kDa
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ID gène
- 2495
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NCBI Accession
- NM_002032, NP_002023
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UniProt
- P02794
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Pathways
- Transition Metal Ion Homeostasis
Antigène
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