FTH1 anticorps (Middle Region)

N° du produit ABIN2785803

Cet anticorps anti-FTH1 est un anticorps Lapin Polyclonal détectant FTH1 dans WB et IHC. Adapté pour Humain, Souris, Rat, Mouton, Chien, Lapin, Cheval, Boeuf (Vache), Cobaye et Chévre. Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour FTH1 anticorps (Middle Region) (ABIN2785803)

Antigène: FTH1 (Ferritin, Heavy Polypeptide 1 (FTH1))

Reactivité: Humain, Souris, Rat, Mouton, Chien, Lapin, Cheval, Boeuf (Vache), Cobaye, Chévre

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FTH1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-FTH1 anticorps

Épitope: Middle Region

Séquence: NVNQSLLELH KLATDKNDPH LCDFIETHYL NEQVKAIKEL GDHVTNLRKM

Homologie: Cow: 93%, Dog: 100%, Goat: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%

Attributs du produit: This is a rabbit polyclonal antibody against FTH1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human FTH1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 183 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-FTH1 (ABIN2785803)

Potrykus, Stead, Maccallum, Urgast, Raab, van Rooijen, Feldmann, Brown: "Fungal iron availability during deep seated candidiasis is defined by a complex interplay involving systemic and local events." dans: PLoS pathogens, Vol. 9, Issue 10, pp. e1003676, (2013) (PubMed).

Détails sur FTH1

Antigène: FTH1 (Ferritin, Heavy Polypeptide 1 (FTH1))

Autre désignation: FTH1

Sujet: FTH1 is the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene encodes the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene has multiple pseudogenes. Several alternatively spliced transcript variants have been observed, but their biological validity has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FTH, FTHL6, MGC104426, PIG15, PLIF, FHC
Protein Interaction Partner: SDCBP, FTL, FTH1, WDYHV1, CEP57, AURKB, TP53, AURKA, ASB15, ASB16, SUPT16H, SET, MAPK9, MAX, IGSF8, TICAM2, HCVgp1, PIAS4, CDC16, YWHAE, SOX5, MYL3, LBP, KPNA2, GRB2, DAXX, CSNK2B, CDC25A, ATP6V1B1, CD99, SPP1, TRAF4, SUMO2, UBC, Cep55, Trim28, NR1I3, NR3
Protein Size: 183

Poids moléculaire: 21 kDa

ID gène: 2495

NCBI Accession: NM_002032, NP_002023

UniProt: P02794

Pathways: Transition Metal Ion Homeostasis